1452840-68-4Relevant articles and documents
Sialyltransferase inhibitors: Consideration of molecular shape and charge/hydrophobic interactions
Kumar, Rishi,Nasi, Ravindranath,Bhasin, Milan,Khieu, Nam Huan,Hsieh, Margaret,Gilbert, Michel,Jarrell, Harold,Zou, Wei,Jennings, Harold J.
, p. 45 - 55 (2013/10/21)
In order to evaluate the importance of molecular shape of inhibitor molecules and the charge/H-bond and hydrophobic interactions, we synthesized three types of molecules and tested them against a sialyltransferase. The first type of compounds were designe