1452864-13-9Relevant articles and documents
Copper(ii)-catalyzed trifluoromethylation of N-aryl imines
Zhang, Yong-Qiang,Liu, Ji-Dan,Xu, Hao
, p. 6242 - 6245 (2013)
Methods for imine trifluoromethylation are of great importance because amines with trifluoromethylated stereogenic centers are useful building blocks for synthetic chemistry and drug discovery. Herein, we describe a new copper(ii)-catalyzed imine trifluoromethylation method without the use of Lewis base activators, presumably through cooperative activation.