1453105-89-9

Basic information

• Product Name: (4S)-3-(3-methylnonanoyl)-4-phenyloxazolidin-2-one
• Synonyms: (4S)-3-(3-methylnonanoyl)-4-phenyloxazolidin-2-one
• CAS NO: 1453105-89-9
• Molecular Weight: 317.428
• Mol File: 1453105-89-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S)-3-(3-methylnonanoyl)-4-phenyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-3-(3-methylnonanoyl)-4-phenyloxazolidin-2-one(1453105-89-9)
• EPA Substance Registry System: (4S)-3-(3-methylnonanoyl)-4-phenyloxazolidin-2-one(1453105-89-9)

Safety Data

• Hazardous Substances Data: 1453105-89-9(Hazardous Substances Data)

Upstream product

• 148766-15-8 (4S)-N-crotonyl-4-phenyloxazolidin-2-one 
• 3761-92-0 n-hexylmagnesium bromide 

Relevant articles and documents

Diastereoselective copper-catalysed 1,4-addition of Grignard reagents to N-enoyl oxazolidinones

Conjugate additions of organometallic reagents to α,β- unsaturated carboxylic acid derivatives give access to numerous β-substituted chiral building blocks. Chiral oxazolidinones serve as useful surrogates of carboxylic function in the asymmetric conjugate addition of Grignard reagents. N-Enoyl oxazolidinones undergo this 1,4-addition with a catalytic amount of copper salt and using either chiral or achiral phosphine ligands. In particular, chiral ferrocenyl phosphane oxazolines proved useful in achieving high diastereoselectivities. The resulting N-acyl oxazolidinones were obtained in good yields and with high diastereoselectivities (up to single diastereomer).