1453853-24-1

Basic information

• Product Name: (S)-1-(2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-((2-methylpyrimidin-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one
• Synonyms: (S)-1-(2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-((2-methylpyrimidin-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one
• CAS NO: 1453853-24-1
• Molecular Weight: 567.138
• Mol File: 1453853-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-(2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-((2-methylpyrimidin-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-((2-methylpyrimidin-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one(1453853-24-1)
• EPA Substance Registry System: (S)-1-(2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-((2-methylpyrimidin-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one(1453853-24-1)

Safety Data

• Hazardous Substances Data: 1453853-24-1(Hazardous Substances Data)

Upstream product

• 1453851-57-4 4-(2-(methylthio)pyrimidin-4-yl)pyridin-2(1H)-one 
• 1453851-73-4 4-(2-fluoropyridin-4-yl)-2-(methylthio)pyrimidine 
• 401815-98-3 2-fluoropyridin-4-ylboronic acid 
• 1453851-79-0 (S)-1-(2-((tert-butyldimethylsilyl)oxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-(methylthio)pyrimidin-4-yl)pyridin-2(1H)-one 
• 74-69-1 2-methyl-pyrimidin-4-ylamine 
• 1453851-69-8 (S)-1-(2-((tert-butyldimethylsilyl)oxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-(methylsulfonyl)pyrimidin-4-yl)-pyridin-2(1H)-one 
• 1453851-59-6 (R)-2-((tert-butyldimethylsilyl)oxy)-1-(4-chloro-3-fluorophenyl)ethyl methanesulfonate 
• 1395078-43-9 (R)-2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethanol 
• 1453854-84-6 (R)-1-(4-chloro-3-fluorophenyl)ethane-1,2-diol 
• 1263414-46-5 1-chloro-2-fluoro-4-vinylbenzene 
• 5527-95-7 4-chloro-3-fluorobenzaldehyde 

Downstream Products

• 1453848-03-7 (S)-1-(1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((2-methylpyrimidin-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one 

Relevant articles and documents

SERINE/THREONINE KINASE INHIBITORS

Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.