1454692-94-4

Basic information

• Product Name: N-(2,5-dimethoxy-4-(phenylcarbamoyl)phenyl)pyrazine-2-carboxamide
• Synonyms: N-(2,5-dimethoxy-4-(phenylcarbamoyl)phenyl)pyrazine-2-carboxamide
• CAS NO: 1454692-94-4
• Molecular Weight: 378.387
• Mol File: 1454692-94-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2,5-dimethoxy-4-(phenylcarbamoyl)phenyl)pyrazine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,5-dimethoxy-4-(phenylcarbamoyl)phenyl)pyrazine-2-carboxamide(1454692-94-4)
• EPA Substance Registry System: N-(2,5-dimethoxy-4-(phenylcarbamoyl)phenyl)pyrazine-2-carboxamide(1454692-94-4)

Safety Data

• Hazardous Substances Data: 1454692-94-4(Hazardous Substances Data)

Upstream product

• 4744-50-7 2,3-pyrazinedicarboxylic anhydride 
• 265332-93-2 4-amino-2,5-dimethoxy-N-phenylbenzamide 

Relevant articles and documents

Preparation of pyrazine carboxamides: A reaction involving N-heterocyclic carbene (NHC) intermediates

In the reactions of 2,3-pyrazinedicarboxylic anhydride with amines and anilines, pyrazine carboxamides are formed in good to excellent yields. A mechanism is proposed involving ring opening of the anhydride and decarboxylation of the heterocyclic ring. Based on other similar heterocyclic decarboxylations, this suggests the involvement of an N-heterocyclic carbene intermediate leading to the product.