145474-76-6Relevant articles and documents
Mimicking of Ergot Alkaloids and Synthetic Piperidine Drugs by 2,5-Substituted Piperidines Derived from Cis and Trans Ethyl 1-Benzyl-6-Cyano-3-Piperidinecarboxylate.
Branden, Stefan Van den,Compernolle, Frans,Hoornaert, Georges J.
, p. 9753 - 9766 (2007/10/02)
This report describes the synthesis of pharmacologically interesting 2,5-substituted piperidines from cis and trans ethyl 1-benzyl-6-cyano-3-piperidinecarboxylate 4.Reduction and p-fluorobenzoylation of 4 led to the primary alcohols 7.The alcohols were tr