145485-03-6

Basic information

• Product Name: (R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER;CARBAMIC ACID, N-[(3R)-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-BENZAZEPIN-3-YL]-, 1,1-DIMETHYLETHYL ESTER;(R)-tert-Butyl (2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)carbaMate
• CAS NO: 145485-03-6
• Molecular Formula: C₁₅H₂₀N₂O₃
• Molecular Weight: 276.33
• Mol File: 145485-03-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 472.454°C at 760 mmHg
• Flash Point: 239.532°C
• Appearance: /
• Density: 1.175g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.556
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER(145485-03-6)
• EPA Substance Registry System: (R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER(145485-03-6)

Safety Data

• Hazardous Substances Data: 145485-03-6(Hazardous Substances Data)

Usage

Description

(R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER is a carbamic acid tert-butyl ester derivative featuring a benzo[b]azepine ring system. This chemical compound serves as a pharmacological intermediate in the synthesis of pharmaceuticals targeting neurological and psychiatric disorders. It has been investigated for its potential therapeutic effects on conditions such as depression, anxiety, and other central nervous system disorders, and is also utilized as a research tool to explore the biochemical and physiological processes associated with these conditions.

Uses

Used in Pharmaceutical Industry:
(R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a pharmacological intermediate for the synthesis of potential drugs aimed at treating neurological and psychiatric disorders. Its application is based on its structural properties that allow for the development of compounds with specific therapeutic effects on the central nervous system.
Used in Research and Development:
In the field of research and development, (R)(2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a research tool to study the biochemical and physiological processes related to depression, anxiety, and other central nervous system disorders. Its application in this context is due to its potential to provide insights into the underlying mechanisms of these conditions, which can contribute to the development of novel therapeutic strategies.

InChI:InChI=1/C15H20N2O3/c1-15(2,3)20-14(19)17-12-9-8-10-6-4-5-7-11(10)16-13(12)18/h4-7,12H,8-9H2,1-3H3,(H,16,18)(H,17,19)/t12-/m1/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 86499-35-6 3-amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 140700-64-7 3-iodo-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 97278-68-7 3-azido-2,3,4,5-tetrahydro-2-oxo-1 H-1-benzazepine 
• 4424-80-0 2,3,4,5-tetrahydro-1H-1-benzo[b]azepin-2-one 
• 156247-60-8 (2-Oxo-2,5-dihydro-1H-benzo[b]azepin-3-yl)-carbamic acid tert-butyl ester 

Downstream Products

• 1310816-87-5 4-chloro-N-[1-[[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamoyl]cyclopropyl]benzamide hydrochloride 
• 1310816-82-0 4-chloro-N-[1-[[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamoyl]cyclopropyl]benzamide 4-methylbenzenesulfonic acid salt 
• 1310817-07-2 benzyl N-((4R)-1-methyl-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl)carbamate 
• 1310817-08-3 benzyl N-((4S)-1-methyl-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl)carbamate 
• 1310816-34-2 N-[1-[[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamoyl]cyclopropyl]-4-fluoro-benzamide 
• 1310817-05-0 benzyl N-[(3R)-2-methylsulfanyl-4,5-dihydro-3H-1-benzazepin-3-yl]carbamate 
• 1310817-03-8 benzyl N-(2-methyl-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl)carbamate 
• 1310817-02-7 benzyl N-[(3R)-1-acetonyl-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]carbamate 
• 1310816-99-9 benzyl N-[(3R)-2-(2,2-dimethoxyethylamino)-4,5-dihydro-3H-1-benzazepin-3-yl]carbamate 
• 1310816-98-8 benzyl N-[(3R)-2-thioxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl]carbamate 
• 1310816-21-7 4-Chloro-N-[1-[[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamoyl]cyclopropyl]benzamide 
• 1310816-20-6 N-[1-[[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamoyl]cyclopropyl]-4-ethoxy-benzamide 
• 1310816-94-4 benzyl N-[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate 
• 1310816-95-5 benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate 

Relevant articles and documents

Benzo-fused lactams promote release of growth hormone

There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused lactams as the active ingredient therefore are also disclosed.

Benzo-fused lactams that promote the release of growth hormone

There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused lactams as the active ingredient thereof are also disclosed.