1455-20-5 Usage
Description
2-N-Butylthiophene is an organic compound with the molecular formula C10H12S. It is a heterocyclic compound that consists of a thiophene ring with a butyl group attached to the nitrogen atom. 2-N-BUTYLTHIOPHENE has potential applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
2-N-Butylthiophene is used as a Glutathione S-transferase inducer for its potential role in enhancing the body's detoxification processes. Glutathione S-transferases are enzymes that help neutralize harmful substances and protect cells from damage.
Used in Cancer Research:
2-N-Butylthiophene is used as an inhibitor of DMH-induced aberrant crypt formation, which is a biomarker for colorectal cancer. By inhibiting this process, it may contribute to the prevention or reduction of colorectal cancer risk.
Used in Anticancer Applications:
2-N-Butylthiophene inhibits tumorigenesis in vivo, making it a potential candidate for the development of anticancer drugs. Its ability to suppress the formation of tumors could lead to new treatments for various types of cancer.
Used as a Chemical Intermediate:
2-N-Butylthiophene serves as a primary and secondary intermediate in the synthesis of various chemicals and materials. Its unique structure allows it to be a valuable building block for creating more complex molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1455-20-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,5 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1455-20:
(6*1)+(5*4)+(4*5)+(3*5)+(2*2)+(1*0)=65
65 % 10 = 5
So 1455-20-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H12S/c1-2-3-5-8-6-4-7-9-8/h4,6-7H,2-3,5H2,1H3
1455-20-5Relevant articles and documents
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Sotoyama et al.
, p. 1865 (1979)
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Ligand assessment for the suzuki-miyaura cross coupling reaction of aryl and heteroaryl bromides with n-butylboronic acid. The advantages of buchwald's s-phos
Jagusch, Thomas,Lehnemann, Bernd,Meudt, Andreas,Nerdinger, Sven,Neuner, Sandro,Scherer, Stefan,Schottenberger, Herwig,Snieckus, Victor
, p. 631 - 644 (2020/01/31)
An investigation of biarylphosphine ligands for the Suzuki-Miyaura cross coupling reaction of aryl and heteroaryl bromides with n-butylboronic acid is presented. The results obtained on ligand modification and aryl as well as heteroaryl bromides variation represent a significant improvement in the state of the art of alkylboronic acid cross coupling methodology.
Palladium-catalyzed regioselective allylation of five-membered heteroarenes with allyltributylstannane
Zhang, Sheng,Yu, Xiaoqiang,Feng, Xiujuan,Yamamoto, Yoshinori,Bao, Ming
supporting information, p. 3842 - 3845 (2015/03/30)
Palladium-catalyzed allylation reactions of 2-(chloromethyl)thiophenes, 2-(chloromethyl)furans, and N-protected 2-(chloromethyl)-1H-pyrroles with allyltributylstannane were described in this study. This type of allylation reaction regioselectively occurred on the heteroarene rings to produce allylated dearomatization products or allylated heteroarenes with satisfactory yields.
