1455091-61-8

Basic information

• Product Name: 4-bromo-2-{[(2,4-dimethoxybenzyl)(ethoxycarbonylmethyl)amino]methyl}benzoic acid ethyl ester
• Synonyms: 4-bromo-2-{[(2,4-dimethoxybenzyl)(ethoxycarbonylmethyl)amino]methyl}benzoic acid ethyl ester
• CAS NO: 1455091-61-8
• Molecular Weight: 494.382
• Mol File: 1455091-61-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-{[(2,4-dimethoxybenzyl)(ethoxycarbonylmethyl)amino]methyl}benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-{[(2,4-dimethoxybenzyl)(ethoxycarbonylmethyl)amino]methyl}benzoic acid ethyl ester(1455091-61-8)
• EPA Substance Registry System: 4-bromo-2-{[(2,4-dimethoxybenzyl)(ethoxycarbonylmethyl)amino]methyl}benzoic acid ethyl ester(1455091-61-8)

Safety Data

• Hazardous Substances Data: 1455091-61-8(Hazardous Substances Data)

Upstream product

• 260561-85-1 4-bromo-2-(bromomethyl)benzoic acid ethyl ester 
• 95218-34-1 ethyl 2-{[(2,4-dimethoxyphenyl)methyl]amino}acetate 

Downstream Products

• 1455091-69-6 1-cyano-7-(2,6-difluorophenoxy)-4-hydroxyisoquinoline-3-carboxylic acid ethyl ester 
• 1455091-72-1 3-{[1-cyano-7-(2,6-difluorophenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino}-2,2-dimethyl-propionic acid tert-butyl ester 
• 1455087-31-6 3-{[1-cyano-7-(2,6-difluorophenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino}-2,2-dimethyl-propionic acid tert-butyl ester 
• 1455091-76-5 7-(4-chloro-3-fluorophenoxy)-4-hydroxyisoquinoline-3-carboxylic acid ethyl ester 
• 1455091-78-7 3-{[7-(4-chloro-3-fluorophenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino}-2,2-dimethylpropionic acid tert-butyl ester 
• 1455087-34-9 3-{[7-(4-chloro-3-fluorophenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino}-2,2-dimethylpropionic acid 
• 1455091-96-9 1-({[1-cyano-7-(2,6-difluorophenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino}methyl)cyclobutanecarboxylic acid tert-butyl ester 
• 1455087-43-0 1-({[1-cyano-7-(2,6-difluorophenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino}methyl)cyclobutanecarboxylic acid 
• 1455092-23-5 7-(2-chloro-5-fluorophenoxy)-4-hydroxyisoquinoline-3-carboxylic acid ethyl ester 
• 1455092-24-6 7-(2-chloro-5-fluorophenoxy)-4-hydroxy-1-iodoisoquinoline-3-carboxylic acid ethyl ester 
• 1455092-27-9 7-(2-chloro-5-fluorophenoxy)-1-cyano-4-hydroxyisoquinoline-3-carboxylic acid ethyl ester 
• 1455092-29-1 3-{[7-(2-chloro-5-fluorophenoxy)-1-cyano-4-hydroxyisoquinoline-3-carbonyl]amino}-2,2-dimethylpropionic acid tert-butyl ester 
• 1455087-53-2 3-{[7-(2-chloro-5-fluorophenoxy)-1-cyano-4-hydroxyisoquinoline-3-carbonyl]amino}-2,2-dimethylpropionic acid 
• 1455089-04-9 5-{[7-(2,6-difluorophenoxy)-4-hydroxyisoquinoline-3-carbonyl]amino}pentanoic acid 

Relevant articles and documents

4 -HYDROXY- ISOQUINOLINE COMPOUNDS AS HIF HYDROXYLASE INHIBITORS

The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds of formula (I) for use in disorders such as muscle degeneration, colitis, IBD, and certain ischemias.