145622-63-5Relevant articles and documents
The Potential of Carbocyclic Nucleosides for the Treatment of Aids: Synthesis of Some Diphosphorylphosphonates Possessing Potent Activity Against HIV-Coded Reverse Transcriptase
Coe, Diane M.,Roberts, Stanley M.,Storer, Richard
, p. 2695 - 2704 (2007/10/02)
The phosphonates 19, 20, 24, 27 and the diphosphorylphosphonates 10 and 11 have been prepared as mimics of nucleoside-phosphates and -triphosphates respectively.The compounds 10 and 11 were found to be potent inhibitors of human immunodeficiency virus rev