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145682-38-8

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145682-38-8 Usage

Uses

(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.

Check Digit Verification of cas no

The CAS Registry Mumber 145682-38-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,6,8 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 145682-38:
(8*1)+(7*4)+(6*5)+(5*6)+(4*8)+(3*2)+(2*3)+(1*8)=148
148 % 10 = 8
So 145682-38-8 is a valid CAS Registry Number.

145682-38-8Downstream Products

145682-38-8Relevant articles and documents

PROCESS FOR THE PREPARATION OF PERINDOPRIL

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Page/Page column 11-12, (2010/02/14)

A process for preparing perindopril (III) or a pharmaceutically acceptable salt thereof, which process comprises a substituted benzyl ester of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid (I) with N-[(S)-carbethoxybutyl]-(S)-alanine (II) where R represents a halo, C1-4 alkoxy or nitro substituent.

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