145736-64-7 Usage
General Description
2,3-DIMETHOXY-THIOBENZAMIDE is a chemical compound with the molecular formula C9H11NO3S. It is a thioamide derivative with two methoxy groups attached to the benzene ring. 2,3-DIMETHOXY-THIOBENZAMIDE is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is known for its versatile reactivity and has been studied for its potential use in medicinal chemistry. 2,3-DIMETHOXY-THIOBENZAMIDE may also have applications as a building block in the development of new materials and chemical processes. However, it is important to handle this compound with care, as it may pose hazards if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 145736-64-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,7,3 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 145736-64:
(8*1)+(7*4)+(6*5)+(5*7)+(4*3)+(3*6)+(2*6)+(1*4)=147
147 % 10 = 7
So 145736-64-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO2S/c1-11-7-5-3-4-6(9(10)13)8(7)12-2/h3-5H,1-2H3,(H2,10,13)
145736-64-7Relevant articles and documents
Novel thiazole derivatives as inhibitors of superoxide production by human neutrophils: Synthesis and structure-activity relationships
Chihiro,Nagamoto,Takemura,Kitano,Komatsu,Sekiguchi,Tabusa,Mori,Tominaga,Yabuuchi
, p. 353 - 358 (2007/10/02)
Neutrophils have an important role in the self-defense systems of organisms through the production of superoxide. On the other hand, it has been proposed that abnormal amounts of superoxide produced by neutrophils are a serious factor in tissue injury. A series of novel thiazole derivatives was prepared and evaluated inhibitory effect on superoxide production by human neutrophils in vitro. Among these compounds, 6-[2-(3,4- diethoxyphenyl)thiazol-4-yl]-pyridine-2-carboxylic acid (OPC-6535) was selected as one of the most promising compounds. The synthesis and structure- activity relationships of these compounds are reported herein.
