1460-13-5Relevant articles and documents
Access to Alkyl-Substituted Lactone via Photoredox-Catalyzed Alkylation/Lactonization of Unsaturated Carboxylic Acids
Sha, Wanxing,Ni, Shengyang,Han, Jianlin,Pan, Yi
, p. 5900 - 5903 (2017)
An efficient photoredox-catalyzed alkylation/lactonization reaction of unsaturated carboxylic acids by using alkyl N-hydroxyphthalimide esters as alkylation reagents has been developed. Varieties of redox-active esters derived from aliphatic carboxylic acids were proved viable in this method, affording alkyl substituted lactones in moderate to good yields. This redox-neutral procedure features mild conditions and operational simplicity, which provides a new strategy for the synthesis of alkyl substituted lactones.
Alkenylation of unactivated alkyl bromides through visible light photocatalysis
Zhou, Quan-Quan,Düsel, Simon Josef Siegfried,Lu, Liang-Qiu,K?nig, Burkhard,Xiao, Wen-Jing
supporting information, p. 107 - 110 (2019/01/03)
Two visible-light driven alkenylation reactions of unactivated alkyl bromides, which were enabled by the use of Ir(dF(CF3)ppy)2(dtbbpy)PF6 as the photocatalyst and (TMS)3SiH as the atom transfer reagent to activate the alkyl bromides, were described for the first time. These protocols can be used to produce a variety of alkenes from easily available feedstock with good reaction efficiency and high chemoselectivity under mild reaction conditions. To further demonstrate the applicability of the present strategy, the alkenylation of bioactive molecules and glycosyl bromides, as well as the alkynylation of unactivated alkyl bromides, was proven to be feasible.
A metal-free yne-addition/1,4-aryl migration/decarboxylation cascade reaction of alkynoates with Csp3-H centers
Kong, De-Long,Cheng, Liang,Wu, Hong-Ru,Li, Yang-Xiong,Wang, Dong,Liu, Li
, p. 2210 - 2217 (2016/03/01)
A metal-free cascade reaction of aryl alkynoates with five different types of radical precursors (R-H) through an yne-addition/1,4-aryl migration/decarboxylation process was reported, which allowed facile and convenient access to functionalized vinyl products with "R" and protons located at the identical carbon of the formed double bond.