146136-78-9 Usage
General Description
2,4-Diaminoquinoline is a chemical compound with the molecular formula C9H8N2. It is a yellow solid that is insoluble in water but soluble in organic solvents. 2,4-Diaminoquinoline is primarily used as a building block in the synthesis of pharmaceuticals, particularly antimalarial drugs. It has also been studied for its potential as a corrosion inhibitor in the oil and gas industry. Additionally, 2,4-Diaminoquinoline is known to exhibit antimicrobial and antifungal properties, making it a useful ingredient in certain industrial and agricultural applications. However,
Check Digit Verification of cas no
The CAS Registry Mumber 146136-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,1,3 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 146136-78:
(8*1)+(7*4)+(6*6)+(5*1)+(4*3)+(3*6)+(2*7)+(1*8)=129
129 % 10 = 9
So 146136-78-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3/c10-7-5-9(11)12-8-4-2-1-3-6(7)8/h1-5H,(H4,10,11,12)
146136-78-9Relevant articles and documents
Regioselective Azidation of 2,4-Dichloroquinolines
Steinschifter, Waltraud,Stadlbauer, Wolfgang
, p. 311 - 318 (2007/10/02)
Reactions of 2,4-dichloroquinolines (2a-f) with sodium azide in DMF lead either regioselectively to 4-azido-2-chloroquinolines (3a-f) or with excess of sodium azide and catalysts to 5-azido-tetrazoloquinolines (4a-f). 2,4-Dichloroquinolines (2g-i) having electron donating substituents in 3-position react with sodium azide in DMF to a mixture of 4-azido-2-chloroquinolines (3g-i) and 5-chlorotetrazoloquinolines (5g-i).When the reaction of the 2,4-dichloroquinolines (2a-i) with sodium azide is carried out in ethanol with addition of methanesulfonic acid, regioselectively 5-chloro-tetrazoloquinolines (5a-i) are obtained.Structural assignments of 3 and 5 have been carried out by 13C-NMR spectra, IR spectra and degradation reactions of the azido- and tetrazolo group to aminoquinolines (7 and 10) via iminophosphoranes (8 and 9).It could be shown that in 2-azido/tetrazolo-quinolines (4 and 5) the tetrazole ring structure is the dominant species.