14621-59-1Relevant articles and documents
Synthesis of coumarin derivatives as inhibitors of platelet aggregation
Chen, Yeh-Long,Wang, Tai-Chi,Lee, Kuan-Han,Tzeng, Cherng-Chyi,Chang, Ya-Ling,Teng, Che-Ming
, p. 651 - 657 (1996)
In a search for the inhibitors of platelet aggregation, certain coumarin derivatives were synthesized and evaluated for antiplatelet activity against thrombin(Thr)-, arachidonic acid(AA)-, collagen(Col)-, and platelet-activating-factor(PAF)-induced aggreg
Synthesis of benzofurans from the cyclodehydration of α-phenoxy ketones mediated by Eaton’s reagent
Ma, Lin,Ma, Zhanwei,Zhang, Min,Zhou, Min
, p. 426 - 436 (2020/03/23)
Cyclodehydration of α-phenoxy ketones promoted by Eaton’s reagent (phosphorus pentoxide–methanesulfonic acid) is used to prepare 3-substituted or 2,3-disubstituted benzofurans with moderate to excellent yields under mild conditions. The method provides a facile access to benzofurans from readily available starting materials such as phenols and α-bromo ketones. The reaction is highly efficient, which is attributed to the good reactivity and fluidity of Eaton’s reagent. The reaction can be applied to prepare naphthofurans, furanocoumarins, benzothiophenes, and benzopyrans.
Discovery of oxime-bearing naphthalene derivatives as a novel structural type of Nrf2 activators
Chang, Ken-Ming,Liang, Fong-Pin,Chen, I-Li,Yang, Shyh-Chyun,Juang, Shin-Hun,Wang, Tai-Chi,Chen, Yeh-Long,Tzeng, Cherng-Chyi
, p. 3852 - 3859 (2015/08/03)
Abstract Recent studies have demonstrated that oxidative stress insult is one of major causes of tumor formation. Therefore, identify the effective anti-oxidative agents as a preventive approach to stop cancer progression has widely explored. Although, ma
