146236-39-7

Basic information

• Product Name: (R)-4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one
• CAS NO: 146236-39-7
• Molecular Weight: 428.439
• Mol File: 146236-39-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(146236-39-7)
• EPA Substance Registry System: (R)-4-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(146236-39-7)

Safety Data

• Hazardous Substances Data: 146236-39-7(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 146236-48-8 (R)-3-(5-methoxy-3,4-methylenedioxybenzyl)butanolide 

Downstream Products

• 58546-54-6 schisandrol B 
• 143503-88-2 (R)-4-(3,4-Dihydroxy-5-methoxy-benzyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one 

Relevant articles and documents

Synthesis of optically pure gomisin A and schizandrin: The first total synthesis of gomisin A and schizandrin having naturally occurring configurations

The total synthesis of gomisin A and schizandrin having natural configurations were accomplished for the first time. The key feature of these syntheses is a highly efficient intramolecular oxidative coupling of the intermediates 9 and 21, which can be obtained as both enantiomers in optically pure forms. The manipulation of the lactone moieties of 7 and 22 afforded natural enantiomers of schizandrin and gomisin A.