146300-27-8Relevant articles and documents
THE CHEMISTRY OF 1,1'-THIOBIS(2-CHLOROETHANE) (SULPHUR MUSTARD) PART II: THE SYNTHESIS OF SOME CONJUGATES WITH CYSTEINE, N-ACYLCYSTEINE AND N-ACETYLCYSTEINE METHYL ESTER
Black, R. M.,Brewster, K.,Clarke, R. J.,Harrison, J. M.
, p. 49 - 58 (2007/10/02)
The syntheses of a number of conjugates of 1,1'-thiobis(2-chloroethane) ("sulphur mustard") and its simple derivatives with cysteine, N-acetylcysteine and N-acetylcysteine methyl ester are described.These compounds were synthesised for use as reference compounds to support metabolite identification in metabolic studies and, in some cases, to provide standards for analytical procedures being developed for the retrospective confirmation of exposure to sulphur mustard. Key words: Thiobis(2-chloroethane) and conjugates with cysteine, N-acetylcysteine and N-acetylcysteine methyl ester; metabolic studies.