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1464-11-5

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1464-11-5 Usage

Description

4-BENZYLOXY-3-INDOLEACETONITRILE is a tryptamine derivative, which is an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. It is characterized by its light brown solid appearance.

Uses

Used in Pharmaceutical Industry:
4-BENZYLOXY-3-INDOLEACETONITRILE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds, particularly the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Its role in the synthesis process is crucial for the development of medications targeting neurological and psychiatric disorders.
Used in Chemical Research:
As a tryptamine derivative, 4-BENZYLOXY-3-INDOLEACETONITRILE is also utilized in chemical research for the exploration of new compounds and their potential applications in various fields, including medicine, agriculture, and materials science. Its unique chemical properties make it a valuable component in the development of novel substances with specific functionalities.

Check Digit Verification of cas no

The CAS Registry Mumber 1464-11-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,6 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1464-11:
(6*1)+(5*4)+(4*6)+(3*4)+(2*1)+(1*1)=65
65 % 10 = 5
So 1464-11-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H14N2O/c18-10-9-14-11-19-15-7-4-8-16(17(14)15)20-12-13-5-2-1-3-6-13/h1-8,11,19H,9,12H2

1464-11-5Relevant articles and documents

Simple one step syntheses of indole-3-acetonitriles from indole-3-carboxaldehydes

Yamada, Fumio,Hashizume, Tomoko,Somei, Masanori

, p. 509 - 516 (1998)

One step conversion method of indole-3-carboxaldehydes into indole-3-acetonitriles is developed. Applying the method, 4-nitro- (7 a), 4-phenyl-(7 b), 4-iodo- (7 c), 4-methoxy- (7 d), and 4-benzyloxyindole-3-acetonitrile (7 e) are available in two steps from indole-3-carboxaldehyde (4).

Facile synthesis of 6-hydroxyindole-3-acetic acid: On the structure of the aromatic subunit of nephilatoxin-1~6

Shinada, Tetsuro,Miyachi, Miki,Itagaki, Yasuhiro,Naoki, Hideo,Yoshihara, Kazuo,Nakajima, Terumi

, p. 7099 - 7102 (2007/10/03)

A facile synthesis of 6-hydroxyindole-3-acetic acid 1a, which is the proposed aromatic subunit of NPTX-1~6, is described. Radical cyclization of isonitrile 2 successfully afforded 9 in high yield. The aromatic subunit of NPTX-1~6 was confirmed as 4-hydroxyindole-3-acetic acid 12 by comparison of the 1H-NMR spectra with those of authentic 4- and 6-hydroxyindole-3-acetic acids.

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