146464-51-9Relevant articles and documents
Oxadiazoles as ester bioisosteric replacements in compounds related to disoxaril. Antirhinovirus activity
Diana,Volkots,Nitz,Bailey,Long,Vescio,Aldous,Pevear,Dutko
, p. 2421 - 2436 (2007/10/02)
A series of 1,2,4-oxadiazoles has been prepared as ester bioisosteres and tested against 15 human rhinovirus serotypes, and the MIC80, the concentration which inhibits 80% or 12 of the serotypes tested, was determined. Homologation of the alkyl