1465-16-3 Usage
Uses
1-Methylpsilocin is a potent and selective SR-2C agonist.
Biological Activity
Potent and selective 5-HT 2C agonist (IC 50 values are 12 and 633 nM for 5-HT 2C and 5-HT 2A receptors respectively). Displays high affinity for the 5-HT 2B receptor (K i = 38 nM) but acts as an inverse agonist. Active in vivo ; inhibits scratching in a mouse model of OCD.
Check Digit Verification of cas no
The CAS Registry Mumber 1465-16-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,6 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1465-16:
(6*1)+(5*4)+(4*6)+(3*5)+(2*1)+(1*6)=73
73 % 10 = 3
So 1465-16-3 is a valid CAS Registry Number.
1465-16-3Relevant articles and documents
3-(2-(AMINOETHYL)-INDOL-4-OL DERIVATIVES, METHODS OF PREPARATION THEREOF, AND THE USE AS 5-HT2 RECEPTOR MODULATORS
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Paragraph 0096; 0099-00100; 00121; 00124-00125, (2021/09/17)
A compound of Formula I, which possesses 5-HT2A and/or 5-HT2c selective receptor activity, but lacks at least some of the undesirable characteristics of 5-HT2B-agonist related activities, is disclosed. Methods of preparing said compo
