146659-60-1Relevant articles and documents
A new mixed-ligand copper(II) complex of (E)-N′-(2- hydroxybenzylidene) acetohydrazide: Synthesis, characterization, NLO behavior, DFT calculation and biological activities
Yousef Ebrahimipour,Sheikhshoaie, Iran,Crochet, Aurelien,Khaleghi, Moj,Fromm, Katharina M.
, p. 267 - 276 (2014)
A tridentate hydrazone Schiff base ligand, (E)-N′-(2- hydroxybenzylidene)acetohydrazide [HL], and its mixed-ligand Cu(II) complex [CuL(phen)], have been synthesized and characterized by elemental analyses, FT-IR, molar conductivity, UV-Vis spectroscopy. The structure of the complex has been determined by X-ray diffraction. This complex has square pyramidal geometry and the positions around central atom are occupied with donor atoms of Schiff base ligand and two nitrogens of 1,10-phenanthroline. Computational studies of compounds were performed by using DFT calculations. The linear polarizabilities and first hyperpolarizabilities of the studied molecules indicate that these compounds can be good candidates of nonlinear optical materials. It is in accordance with experimental data. In addition, invitro antimicrobial results show that these compounds specially [CuL(phen)] have great potential of antibacterial activity against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Listeria monocytogenes bacteria and antifungal activity against Candida Albicans in comparison to some standard drugs.
Two new hydrogen-bonded supramolecular dioxo-molybdenum(VI) complexes based on acetyl-hydrazone ligands: Synthesis, crystal structure and DFT studies
Bauzá, Antonio,Frontera, Antonio,Maiti, Monami,Pilet, Guillaume,Thakurta, Santarupa
, (2021)
Two new cis-dioxomolybdenum(VI) complexes [MoO2L1(H2O)] (1) and [MoO2L2(H2O)] (2) have been synthesized using two different tridentate hydrazone Schiff base ligands, L1H2/s
Diazaborines oxidize slowly with H2O2 but rapidly with peroxynitrite in aqueous buffer
Domaille, Dylan W.,Golzwarden, Julian V. A.,Haggett, Jack G.,Han, Gun Su,Moser, Angela R.,Vyas, Shubham
supporting information, p. 995 - 999 (2022/02/16)
Reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) and peroxynitrite (ONOO?) oxidize arylboronic acids to their corresponding phenols. When used in molecular imaging probes and in ROS-responsive molecules, however, simple arylboronic acids struggle to discriminate between H2O2 and ONOO? because of their fast rate of reaction with both ROS. Here, we show that diazaborines (DABs) react slowly with H2O2 but rapidly with peroxynitrite in an aqueous buffer. In addition to their slow reaction with H2O2, the immediate product of DAB oxidation with H2O2 and ONOO? can yield a kinetically trapped CN Z-isomer that slowly equilibrates with its E-isomer. Taken together, our work shows that diazaborines exhibit enhanced kinetic discrimination between H2O2 and ONOO? compared to arylboronic acids, opening up new opportunities for diazaborine-based tools in chemical biology.
Mixed-ligand Cu(II) hydrazone complexes designed to enhance anticancer activity
Mo, QingYou,Deng, JunGang,Liu, Yani,Huang, GuiDong,Li, ZuoWen,Yu, Ping,Gou, Yi,Yang, Feng
supporting information, p. 368 - 380 (2018/07/25)
The ligand quantity, ligand type, and coordination geometry have important influences on the anticancer activity of metal-based complexes. On the basis of the structures of previously reported 1:1 Cu(II)/ligand complexes ([Cu(L1)Cl]·2H2O 1a, [C