14678-95-6

Basic information

• Product Name: 5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE&
• Synonyms: 5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE&;5-Amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid;5-Amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid 97%
• CAS NO: 14678-95-6
• Molecular Formula: C₁₁H₁₁N₃O₃
• Molecular Weight: 233.23
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Pyrazoles
• Mol File: 14678-95-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 180-185 °C (dec.)(lit.)
• Boiling Point: 462.2 °C at 760 mmHg
• Flash Point: 233.4 °C
• Appearance: /
• Density: 1.41 g/cm³
• Vapor Pressure: 2.42E-09mmHg at 25°C
• Refractive Index: 1.646
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 4.50±0.10(Predicted)
• CAS DataBase Reference: 5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE&(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE&(14678-95-6)
• EPA Substance Registry System: 5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE&(14678-95-6)

Safety Data

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 14678-95-6(Hazardous Substances Data)

Usage

General Description

5-Amino-1-(4-methoxyphenyl)-1H-pyrazole is a chemical compound with the molecular formula C10H10N4O. It is a pyrazole derivative with a substituted phenyl group, and it is used in pharmaceutical research as a building block for the synthesis of various biologically active compounds. The 4-methoxyphenyl group attached to the pyrazole ring provides potential for modulating the compound's properties and activities. This chemical may have applications in the development of new drugs or therapeutic agents due to its unique structure and potential biological activity. Further research and testing are required to fully understand the potential uses and implications of 5-amino-1-(4-methoxyphenyl)-1H-pyrazole.

InChI:InChI=1/C11H11N3O3/c1-17-8-4-2-7(3-5-8)14-10(12)9(6-13-14)11(15)16/h2-6H,12H2,1H3,(H,15,16)

Upstream product

• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 15001-13-5 ethyl 5-amino-1-(4-methoxy)phenyl-1H-pyrazole-4-carboxylate 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 116884-63-0 (5-amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carboxamide) 

Downstream Products

• 1023312-85-7 5-amino-1-(4-methoxy-phenyl)-1H-pyrazole-4-carboxylic acid (2-methyl-5-(3-trifluoromethyl-benzoylamino)-phenyl)-amide 

Relevant articles and documents

Synthesis of pyrazole-carboxamides and pyrazole-carboxylic acids derivatives: Simple methods to access powerful building blocks

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

3-AMINO-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES USEFUL AS INHIBITORS OF PROTEIN KINASES

The invention relates to novel heterocyclic compounds of the formula (I), in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their use as medicaments and to medicaments comprising them