14686-61-4

Basic information

• Product Name: N-Formyldemecolcine
• Synonyms: (S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylformylamino)benzo[a]heptalene-9(5H)-one;(S)-7-(N-Methyl-N-formylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one;N-Formyldemecolcine
• CAS NO: 14686-61-4
• Molecular Formula: C₂₂H₂₅NO₆
• Molecular Weight: 399.44
• Mol File: 14686-61-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 705.1°C at 760 mmHg
• Flash Point: 380.2°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 9.98E-20mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: N-Formyldemecolcine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Formyldemecolcine(14686-61-4)
• EPA Substance Registry System: N-Formyldemecolcine(14686-61-4)

Safety Data

• Hazardous Substances Data: 14686-61-4(Hazardous Substances Data)

Usage

Description

N-Formyldemecolcine is an alkaloid that has been isolated from various plant sources, including the seeds and corms of Colchicum autumnale, C. cornigerum, Gloriosa virescens, and Littoria modesta. It is characterized by its specific rotation values and melting points, which vary depending on the source from which it is derived.

Uses

Used in Pharmaceutical Industry:
N-Formyldemecolcine is used as a pharmaceutical compound for its potential therapeutic applications. Its isolation from various plant sources indicates its potential for use in the development of new drugs or treatments.
Used in Research and Development:
Due to its unique properties and the variation in its characteristics depending on the source, N-Formyldemecolcine is also used as a subject of research and development. This can lead to a better understanding of its chemical properties, potential applications, and possible integration into various industries.
Used in Chemical Analysis:
The specific rotation values and melting points of N-Formyldemecolcine make it a useful compound for chemical analysis and comparison. It can be used as a reference or standard in the study of other alkaloids and related compounds.

References

Potesilova, Hrbek, Santavy, Collect. Czech. Chern. Commun., 32,141 (1967)Potesilova et al., ibid, 34, 3540 (1969)

InChI:InChI=1/C22H25NO6/c1-23(12-24)16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-12,16H,6,8H2,1-5H3/t16-/m0/s1

Upstream product

• 477-30-5 (-)-demecolcine 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 477-30-5 (-)-demecolcine 

Relevant articles and documents

Facile conversion of natural colchicine into (±)-congeners and (+)-enantiomers including 2-demethyl analogues

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