147091-70-1

Basic information

• Product Name: tert-butyl (S)-1-(Methoxycarbonyl)- 2-cyanoethylcarbaMate
• Synonyms: tert-butyl (S)-1-(Methoxycarbonyl)- 2-cyanoethylcarbaMate
• CAS NO: 147091-70-1
• Molecular Formula: C10H16N2O4
• Molecular Weight: 228.24504
• Mol File: 147091-70-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: tert-butyl (S)-1-(Methoxycarbonyl)- 2-cyanoethylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (S)-1-(Methoxycarbonyl)- 2-cyanoethylcarbaMate(147091-70-1)
• EPA Substance Registry System: tert-butyl (S)-1-(Methoxycarbonyl)- 2-cyanoethylcarbaMate(147091-70-1)

Safety Data

• Hazardous Substances Data: 147091-70-1(Hazardous Substances Data)

Usage

Description

Tert-butyl (S)-1-(Methoxycarbonyl)-2-cyanoethylcarbaMate is a chemical compound with the molecular formula C12H19N3O4. It is a derivative of tert-butyl carbamate and contains a cyano group and a methoxycarbonyl group. tert-butyl (S)-1-(Methoxycarbonyl)-
2-cyanoethylcarbaMate is characterized by its unique structural features and reactivity, making it a valuable tool in organic synthesis and pharmaceutical research.
Usage:
Used in Organic Synthesis:
Tert-butyl (S)-1-(Methoxycarbonyl)-2-cyanoethylcarbaMate is used as an intermediate or building block in organic synthesis for the synthesis of various bioactive molecules. Its unique structural features and reactivity make it a valuable component in the creation of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, tert-butyl (S)-1-(Methoxycarbonyl)-2-cyanoethylcarbaMate is used as a key intermediate in the development of new pharmaceuticals. Its stereochemistry and functional groups contribute to the design and synthesis of innovative drugs and functional materials with potential therapeutic applications.

Upstream product

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Relevant articles and documents

Repurposing Nonheme Iron Hydroxylases to Enable Catalytic Nitrile Installation through an Azido Group Assistance

Three mononuclear nonheme iron and 2-oxoglutarate dependent enzymes, l-Ile 4-hydroxylase, l-Leu 5-hydroxylase and polyoxin dihydroxylase, are previously reported to catalyze the hydroxylation of l-isoleucine, l-leucine, and l-α-amino-δ-carbamoylhydroxyvaleric acid (ACV). In this study, we showed that these enzymes can accommodate leucine isomers and catalyze regiospecific hydroxylation. On the basis of these results, as a proof-of-concept, we demonstrated that the outcome of the reaction can be redirected by installation of an assisting group within the substrate. Specifically, instead of canonical hydroxylation, these enzymes can catalyze non-native nitrile group installation when an azido group is introduced. The reaction is likely to proceed through C - H bond activation by an Fe(IV)-oxo species, followed by azido-directed C-N bond formation. These results offer a unique opportunity to investigate and expand the reaction repertoire of Fe/2OG enzymes.

Synthesis of a key precursor for orienticin C and model study on ruthenium-mediated macrocyclization

(Chemical Equation Presented) A tripeptido-arene-ruthenium complex was prepared as a key precursor for the projected synthesis of orienticin C, demonstrating that the cyclopentadienylruthenium moiety can be attached to a chloroarene in the presence of mul