147128-79-8Relevant articles and documents
Process for Preparing Enantiomerically Enriched Oxamides
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Paragraph 0062; 0063, (2015/07/15)
The present invention relates to a chiral oxamide of formula (I) useful as an intermediate in the preparation of dorzolamide, and to the preparation thereof. The invention also relates to the preparation of dorzolamide, to the hydrochloride salt thereof, and to the active ingredient contained in a drug useful in the treatment of glaucoma, by means of the intermediate of formula (I).