1472-85-1

Basic information

• Product Name: Propanedioic acid,2-octyl-, 1,3-diethyl ester
• Synonyms: Malonicacid, octyl-, diethyl ester (6CI,7CI,8CI); Propanedioic acid, octyl-, diethylester (9CI); Diethyl 2-octylmalonate; Diethyl n-octylmalonate; Diethyloctylmalonate; NSC 74080
• CAS NO: 1472-85-1
• Molecular Formula: C₁₅H₂₈O₄
• Molecular Weight: 272.3804
• Mol File: 1472-85-1.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 304.3°C at 760 mmHg
• Flash Point: 134.7°C
• Appearance: /
• Density: 0.96g/cm³
• Vapor Pressure: 0.000884mmHg at 25°C
• Refractive Index: 1.442
• CAS DataBase Reference: Propanedioic acid,2-octyl-, 1,3-diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid,2-octyl-, 1,3-diethyl ester(1472-85-1)
• EPA Substance Registry System: Propanedioic acid,2-octyl-, 1,3-diethyl ester(1472-85-1)

Safety Data

• Hazardous Substances Data: 1472-85-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H28O4/c1-4-7-8-9-10-11-12-13(14(16)18-5-2)15(17)19-6-3/h13H,4-12H2,1-3H3

Upstream product

• 111-83-1 1-bromo-octane 
• 105-53-3 diethyl malonate 
• 124-13-0 Octanal 
• 140230-54-2 ethyl 2-ethoxycarbonyl-1-decenoate 
• 111-66-0 oct-1-ene 
• 92303-29-2 CH(CO₂C₂H₅)2 
• 103514-65-4 C₁₄H₃₅N₃PS⁽¹⁺⁾ 
• 29330-87-8 Diethyl-2,7-octadienyl-malonat 
• 996-82-7 sodium diethylmalonate 
• 629-27-6 1-Iodooctane 
• 110-38-3 decanoic acid ethyl ester 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 74971-70-3 2-n-octylpropane-1,3-diol 
• 760-55-4 octylmalonic acid 
• 45235-48-1 2-octyl-1-decanol 
• 619-39-6 2-octyldecanoic acid 
• 62716-49-8 α-deuterated decanoic acid 
• 24251-93-2 2,2-dioctylmalonic acid diethyl ester 
• 14077-85-1 5-octylbarbituric acid 
• 75500-18-4 2-benzyloxy-3-methyl-7-methylenepentadecane 
• 1472-09-9 n-octylcyclopropane 
• 81231-47-2 4-(5-Octyl-[1,3]dioxan-2-yl)-benzoic acid 4-cyano-phenyl ester 
• 81231-47-2 4-(5-Octyl-[1,3]dioxan-2-yl)-benzoic acid 4-cyano-phenyl ester 
• 81221-31-0 N-[4-(5-Octyl-[1,3]dioxan-2-yl)-phenyl]-acetamide 
• 81221-31-0 N-[4-(5-Octyl-[1,3]dioxan-2-yl)-phenyl]-acetamide 
• 81221-23-0 5-Octyl-2-(4-pentyloxy-phenyl)-[1,3]dioxane 

Relevant articles and documents

Synthesis and Solution Properties of a Double-Tailed Quaternary Ammonium Surfactant with a Protrudent Head Group

Modification of the molecular structure of surfactants is an effective method for exploring their self-assembly. A double-tailed quaternary ammonium surfactant with a protrudent head group, namely 2-octyldecyltrimethylammonium bromide (2-ODTAB) was synthesized, and the solution properties were investigated by surface tension, dynamic light scattering, and cryogenic TEM. A comparative study was also performed on the traditional double-tailed homologue surfactants dioctyldimethylammonium bromide (8-8), didecyldimethylammonium bromide (10-10), and didodecyldimethylammonium bromide (12-12). The results showed that 2-ODTAB was more effective at lowering surface tension and in forming stable vesicles than traditional double-tailed surfactants with similar alkyl chain length. The reason is attributed to the improved structure of 2-ODTAB, in which the two alkyl tails are connected to the ionic head group by one carbon atom. This structure imparts more freedom to the head group and thus favors formation of more stable aggregates at low concentration. In addition, the lower limit of the alkyl chain length of the double-tailed surfactants for forming stable vesicles was illustrated.

Preparation of mono-substituted malonic acid half oxyesters (SMAHOs)

The use of mono-substituted malonic acid half oxyesters (SMAHOs) has been hampered by the sporadic references describing their preparation. An evaluation of different approaches has been achieved, allowing to define the best strategies to introduce diversity on both the malonic position and the ester function. A classical alkylation step of a malonate by an alkyl halide followed by a monosaponification gave access to reagents bearing different substituents at the malonic position, including functionalized derivatives. On the other hand, the development of a monoesterification step of a substituted malonic acid derivative proved to be the best entry for diversity at the ester function, rather than the use of an intermediate Meldrum acid. Both these transformations are characterized by their simplicity and efficiency, allowing a straightforward access to SMAHOs from cheap starting materials.

Direct Copper-Catalyzed C-H Monofluoroalkylation of Benzoxazoles with 1-Fluoro-1-haloalkanes

The first example of direct C–H bond monofluoroalkylation with 1-fluoro-1-haloalkanes with no adjacent functional groups and with β-hydrogens has been developed. This transformation offers a straightforward route for the synthesis of a series of monofluoroalkylated benzoxazoles.

NOVEL XYLENE-BASED AMPHIPHILIC COMPOUND AND USE THEREOF

The present invention relates to a xylene-based amphiphilic compound, a method for preparing the same, and a method for extracting, solubilizing, stabilizing or crystallizing a membrane protein using the same. By using the xylene-based compound according to the present invention, a membrane protein may be stably stored in an aqueous solution for a long time, and may be applied in functional and structural analyses. The structural and functional analysis of the membrane protein is one of the fields of highest interest in biology and chemistry, and the xylene-based compound according to the present invention can be applied in research on protein structure that is closely related to development of a new drug.