147322-38-1

Basic information

• Product Name: 1-[4-(2-cyclohexylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-(3,4-methylenedioxyphenyl)-1-butene
• Synonyms: 1-[4-(2-cyclohexylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-(3,4-methylenedioxyphenyl)-1-butene
• CAS NO: 147322-38-1
• Molecular Weight: 485.623
• Mol File: 147322-38-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(2-cyclohexylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-(3,4-methylenedioxyphenyl)-1-butene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(2-cyclohexylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-(3,4-methylenedioxyphenyl)-1-butene(147322-38-1)
• EPA Substance Registry System: 1-[4-(2-cyclohexylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-(3,4-methylenedioxyphenyl)-1-butene(147322-38-1)

Safety Data

• Hazardous Substances Data: 147322-38-1(Hazardous Substances Data)

Upstream product

• 147322-25-6 1-[4-(3-dimethylamino-2-hydroxypropoxy)phenyl]-1-phenyl-2-(3,4-methylenedioxyphenyl)-1-butene 
• 108-91-8 cyclohexylamine 
• 91221-46-4 1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene 

Relevant articles and documents

TRIPHENYLETHYLENE DERIVATIVE AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME

A triphenylalkene derivative represented by general formula (1), a pharmaceutically acceptable acid addition salt thereof, and a pharmaceutical composition thereof having a tumor inhibitory action and an osteoporosis curing activity. In general formula (1) R1 represents a group selected among those represented by formulae (2), (3) and (4); R6 and R7 represent each hydrogen, alkyl or cycloalkyl, or R6 and R7 together form a heterocyclic group with the adjacent nitrogen atom, provided that R6 and R7 should not be hydrogen atoms at the same time; R8 represents hydrogen or alkylcarbonyl; R2 represents alkyl or cycloalkyl; R3 represents phenyl or 3,4-methylenedioxyphenyl, provided that when R3 represents phenyl, the case where R1 represents a group of formula (4) is excluded; R4 represents hydrogen, hydroxyl, R9C(O)O-, R10OCH2O-, -OPO(OH)2 or CH = NOR11; R9 represents alkyl; R10 represents alkyl or alkylcarbonyl; R5 represents hydrogen or CH = NOR11; and R11 represents hydrogen, alkyl or substituted alkyl.