14736-30-2 Usage
Description
2-Ethylchromone, also known as ethylchromone, is a chemical compound with the molecular formula C12H10O2. It belongs to the class of organic compounds known as chromones, which are characterized by their benzo-alpha-pyrone structure. 2-Ethylchromone is primarily used in the synthesis of various pharmaceuticals and has been found to exhibit a range of biological activities, including anticonvulsant, antioxidant, and antiproliferative properties. Additionally, it has been studied for its potential as an anti-inflammatory and neuroprotective agent, making it of interest to researchers in the fields of medicinal chemistry and drug development.
Uses
Used in Pharmaceutical Synthesis:
2-Ethylchromone is used as a key intermediate in the synthesis of various pharmaceuticals for its versatile chemical structure and potential to be modified for specific therapeutic applications.
Used in Medicinal Chemistry Research:
2-Ethylchromone is used as a subject of study for its anticonvulsant, antioxidant, and antiproliferative properties, contributing to the development of new treatments for a variety of conditions.
Used in Drug Development:
2-Ethylchromone is used as a potential agent in drug development for its anti-inflammatory and neuroprotective properties, indicating its potential use in managing inflammatory diseases and neurodegenerative conditions.
Used in Antioxidant Applications:
2-Ethylchromone is used as an antioxidant agent for its ability to combat oxidative stress, which is implicated in many diseases and aging processes.
Used in Antiproliferative Applications:
2-Ethylchromone is used as an antiproliferative agent to inhibit the proliferation of cells, particularly in the context of cancer treatment to prevent tumor growth.
Used in Neuroprotection:
2-Ethylchromone is used as a neuroprotective agent to safeguard neurons from damage or degeneration, which is crucial in the treatment of neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 14736-30-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,7,3 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 14736-30:
(7*1)+(6*4)+(5*7)+(4*3)+(3*6)+(2*3)+(1*0)=102
102 % 10 = 2
So 14736-30-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H10O2/c1-2-8-7-10(12)9-5-3-4-6-11(9)13-8/h3-7H,2H2,1H3
14736-30-2Relevant articles and documents
Synthesis of chiral chromanols: Via a RuPHOX-Ru catalyzed asymmetric hydrogenation of chromones
Ma, Yujie,Li, Jing,Ye, Jianxun,Liu, Delong,Zhang, Wanbin
supporting information, p. 13571 - 13574 (2019/01/05)
Chiral chromanols and their derivatives have been synthesized via a RuPHOX-Ru catalyzed asymmetric hydrogenation of chromones in high yields, >20:1 drs and with up to 99.9% ee. Control experiments show that the reaction undergoes two sequential asymmetric hydrogenation steps of the CC and CO double bonds. The reaction could be performed on a gram-scale with a relatively low catalyst loading (up to 1000 S/C), and the resulting products can be transformed to several biologically active compounds.
K2CO3-catalyzed synthesis of chromones and 4-quinolones through the cleavage of aromatic C-O bonds
Zhao, Jie,Zhao, Yufen,Fu, Hua
supporting information; experimental part, p. 2710 - 2713 (2012/07/16)
Phenol-derived electrophiles are favorable substrates because phenols are naturally abundant or can be readily prepared from other aromatic compounds. However, the cleavage of aromatic C-O bonds is a great challenge because of their high energy. K2CO3-catalyzed intramolecular cyclization of 1-(2-alkoxyphenyl)-3-akylpropane-1,3-dione and 3-(alkylimino)-1-(2-methoxyphenyl)-2-methylpropan-1-one derivatives via the selective cleavage of aromatic C-O bonds is reported. The corresponding chromone and 4-quinolone derivatives were obtained in reasonable yields.
A Novel Synthesis of 4H-Chromen-4-ones via Intramolecular Wittig Reaction
Kumar, Pradeep,Bodas, Mandar S.
, p. 3821 - 3823 (2007/10/03)
formula presented The acylphosphoranes formed in a sequential manner from the reaction of the silyl ester of O-acyl(aroyl)salicylic acids and (trimethylsilyl)-methylenetriphenylphosphorane undergo intramolecular Wittig cyclization on the ester carbonyl to afford the 4H-chromen-4-ones in good to excellent yields.
