147821-43-0

Basic information

• Product Name: N-(4-bromophenyl)-4-cyanobenzamide
• Synonyms: N-(4-bromophenyl)-4-cyanobenzamide
• CAS NO: 147821-43-0
• Molecular Weight: 301.142
• Mol File: 147821-43-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(4-bromophenyl)-4-cyanobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromophenyl)-4-cyanobenzamide(147821-43-0)
• EPA Substance Registry System: N-(4-bromophenyl)-4-cyanobenzamide(147821-43-0)

Safety Data

• Hazardous Substances Data: 147821-43-0(Hazardous Substances Data)

Upstream product

• 6068-72-0 4-cyanobenzoyl chlorIde 
• 106-40-1 4-bromo-aniline 
• 619-58-9 4-iodobenzoic acid 
• 150-13-0 4-amino-benzoic acid 
• 619-44-3 methyl 4-iodobenzoate 
• 1711-02-0 4-iodobenzoic acid chloride 
• 619-65-8 4-cyanobenzoic Acid 
• 33554-73-3 1-bromo-4-isocyanobenzene 
• 105-07-7 4-cyanobenzaldehyde 
• 62-53-3 aniline 
• 17922-96-2 4-cyanobenzanilide 

Relevant articles and documents

Aromatase inhibitors: Synthesis, biological activity, and binding mode of azole-type compounds

The enantiomers of the potent nonsteroidal inhibitor of aromatase fadrozole hydrochloride 3 have been separated and their absolute configuration determined by X-ray crystallography. On the basis of a molecular modeling comparison of the active enantiomer

Copper-catalyzed synthesis of arylcarboxamides from aldehydes and isocyanides: The isocyano group as an N1 synthon

An interesting radical coupling reaction of aromatic aldehydes with isocyanides was disclosed for the synthesis of amides catalyzed by copper. According to the experimental results and mechanistic study, the isocyano group acted as an N1 synthon rather than exhibiting the carbene-like reactivity, exploiting a new reactivity profile of isocyanides.

Combining Eosin y with Selectfluor: A Regioselective Brominating System for Para-Bromination of Aniline Derivatives

A mild, metal-free, and absolutely para-selective bromination of aniline derivatives has been developed in excellent yields, wherein the organic dye Eosin Y is employed as the bromine source in company with Selectfluor. Neither air nor moisture sensitive, this facile reaction proceeds smoothly at room temperature and completes within a short time. Mechanistic studies indicate a radical pathway; therefore, the existence of an in situ generated brominating reagent, "Selectbrom", is postulated, which may reasonably account for the unique regioselectivity for the para-bromination of N-acyl- as well as N-sulfonylanilines.