147834-55-7Relevant articles and documents
Manganese complex-catalysed α-alkylation of ketones with secondary alcohols enables the synthesis of β-branched carbonyl compounds
Waiba, Satyadeep,Jana, Sayan K.,Jati, Ayan,Jana, Akash,Maji, Biplab
, p. 8376 - 8379 (2020)
Herein, β-branched carbonyl compounds were synthesised via the α-alkylation of ketones with secondary alcohols under "borrowing hydrogen"catalysis. A wide range of secondary alcohols, including various cyclic, acyclic, symmetrical, and unsymmetrical alcohols, have been successfully applied under the developed reaction conditions. A manganese(i) complex bearing a phosphine-free multifunctional ligand catalysed the reaction and produced water as the sole byproduct.
Iron-Catalyzed α-Alkylation of Ketones with Secondary Alcohols: Access to β-Disubstituted Carbonyl Compounds
Bettoni, Léo,Gaillard, Sylvain,Renaud, Jean-Luc
supporting information, (2020/03/13)
An iron-catalyzed borrowing hydrogen strategy has been applied in the synthesis of β-branched carbonyl compounds. Various secondary benzylic and aliphatic alcohols have been used as alkylating reagents under mild reaction conditions. The ketones have been
Α-Alkylation of Ketones with Secondary Alcohols Catalyzed by Well-Defined Cp*CoIII-Complexes
Chakraborty, Priyanka,Gangwar, Manoj Kumar,Emayavaramban, Balakumar,Manoury, Eric,Poli, Rinaldo,Sundararaju, Basker
, p. 3463 - 3467 (2019/07/05)
Although α-alkylation of ketones with primary alcohols by transition-metal catalysis is well-known, the same process with secondary alcohols is arduous and complicated by self-condensation. Herein a well-defined, high-valence cobalt(III)-catalyst was applied for successful α-alkylation of ketones with secondary alcohols. A wide-variety of secondary alcohols, which include cyclic, acyclic, symmetrical, and unsymmetrical compounds, was employed as alkylating agents to produce β-alkyl aryl ketones.