14802-36-9

Basic information

• Product Name: DIMETHYL-D 6-AMINE
• Synonyms: DIMETHYL-D 6-AMINE;DIMETHYLAMINE (D6);DIMETHYL-D6-AMINE, 99 ATOM % D;Dimethyl-D6-amine (gas);Methan-d3-amine, N-(methyl-d3)-
• CAS NO: 14802-36-9
• Molecular Formula: C₂H₇N
• Molecular Weight: 51.12
• Product Categories: Alphabetical Listings;Chemical Synthesis;Compressed and Liquefied GasesStable Isotopes;DStable Isotopes;Gases;Synthetic Reagents
• Mol File: 14802-36-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: −93 °C(lit.)
• Boiling Point: 7 °C(lit.)
• Appearance: /
• Density: 0.726g/cm³
• Vapor Density: 1.55 (15 °C, vs air)
• Vapor Pressure: 1277 mm Hg ( 20 °C)
• Refractive Index: 1.344
• CAS DataBase Reference: DIMETHYL-D 6-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL-D 6-AMINE(14802-36-9)
• EPA Substance Registry System: DIMETHYL-D 6-AMINE(14802-36-9)

Safety Data

• Hazard Codes: F,C,F+
• Statements: 11-20/21/22-34-20/22-12
• Safety Statements: 16-26-27-36/37/39-45-29-3
• RIDADR: UN 1032 2.1
• WGK Germany: 3
• Hazardous Substances Data: 14802-36-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C2H7N/c1-3-2/h3H,1-2H3/i1D3,2D3

Upstream product

• 4472-41-7 d₇-N,N-dimethylformamide 
• 100-46-9 benzylamine 
• 97941-90-7 N,N-Bis-(D₃-methyl)-p-toluolsulfonamid 

Downstream Products

• 31591-08-9 N,N-dimethylacetamide-d6 
• 185990-36-7 N,N-dimethyl-d₆-formamide 
• 1109219-38-6 d17-2-dimethylaminomethyl-cyclohexanone 
• 144642-49-9 2-{2-(dimethyl-d6-aminomethyl)phenyl}-4,4-diphenyl-1,3,2-dioxaborolane 
• 959605-90-4 D6-zolpidem 
• 194930-03-5 (R,S)-3-[(1-di(2H3)methylamino)ethyl]phenol 

Relevant articles and documents

Method for preparing deuterated methylamine salt through photocatalysis

The invention discloses a method for preparing deuterated methylamine salt through photocatalysis, and relates to the technical field of deuterated synthesis. The method for preparing the deuterated methylamine salt through photocatalysis comprises the following steps: S1, reacting a benzylamine compound with deuterated methanol under the action of a semiconductor photocatalyst at room temperature to obtain an N-deuterated methyl benzylamine compound; and S2, carrying out catalytic hydrogenation debenzylation on the N-deuterium methyl benzylamine compound in a hydrogen atmosphere under the action of a solvent, acid and a catalyst to obtain the deuterated methylamine salt. According to the method provided by the invention, cheap deuterated methanol is used as a deuterium source, the semiconductor photocatalyst is used for catalyzing deuteration, the reaction condition is mild, the yield is high, the deuteration rate can reach 100%, the operation is simple and convenient, and the cost is low; the deuterated methylamine or deuterated dimethylamine hydrochloride can be conveniently and quickly regulated and synthesized by controlling the number of benzyl groups; the synthesized product deuterated methylamine salt can be used as a deuterated building block to be widely applied to synthesis of deuterated drugs, so that the synthesis cost of the deuterated drugs is further reduced, and the deuterated methylamine salt has industrial value.

Transformylating amine with DMF to formamide over CeO2 catalyst

We here report a new protocol for the formylation of various amines, primary or secondary, aromatic or alkyl, cyclic or linear, mono- or di-amine, with dimethylformamide (DMF) as the formylation reagent to obtain the corresponding formamides in good to excellent yields over CeO2 catalyst. The reaction requires no homogeneous acidic or basic additives and is tolerant to water.