1485-72-9

Basic information

• Product Name: N-BENZHYDRYL-BENZAMIDE
• Synonyms: N-BENZHYDRYL-BENZAMIDE
• CAS NO: 1485-72-9
• Molecular Formula: C₂₀H₁₇NO
• Molecular Weight: 287.36
• Mol File: 1485-72-9.mol
• Article Data: 86

Chemical Properties

• Boiling Point: 512°Cat760mmHg
• Flash Point: 310°C
• Appearance: /
• Density: 1.129g/cm³
• Vapor Pressure: 1.34E-10mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: N-BENZHYDRYL-BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZHYDRYL-BENZAMIDE(1485-72-9)
• EPA Substance Registry System: N-BENZHYDRYL-BENZAMIDE(1485-72-9)

Safety Data

• Hazardous Substances Data: 1485-72-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 10, p. 927, 1969 DOI: 10.1017/S0009838800024678

InChI:InChI=1/C20H17NO/c22-20(18-14-8-3-9-15-18)21-19(16-10-4-1-5-11-16)17-12-6-2-7-13-17/h1-15,19H,(H,21,22)

Upstream product

• 100727-40-0 nitric acid benzhydryl ester 
• 55-21-0 benzamide 
• 844-40-6 diphenylmethanol trifluoroacetate 
• 10374-29-5 N-benzylidenebenzamide 
• 143-66-8 sodium tetraphenyl borate 
• 1585-45-1 N-(diphenylmethylene)benzamide 
• 103-72-0 phenyl isothiocyanate 
• 90-99-3 diphenylchloromethane 
• 65-85-0 benzoic acid 
• 91-01-0 1,1-Diphenylmethanol 
• 100-47-0 benzonitrile 
• 91-00-9 Benzhydrylamine 
• 934-56-5 trimethyl(phenyl)stannane 
• 51608-62-9 (E)-N-benzylidenebenzamide 

Downstream Products

• 65-85-0 benzoic acid 
• 62506-88-1 N-benzylidenediphenylmethanamine 
• 5467-43-6 1,3,3-triphenylpropyne 
• 1409940-90-4 2-benzhydryl-3-octyl-3H-inden-5-yl-4-methylbenzenesulfonate 
• 19672-37-8 3-benzhydryl-pentane-2,4-dione 
• 1013-88-3 Benzophenone imine 
• 100-47-0 benzonitrile 
• 90-99-3 diphenylchloromethane 
• 1585-45-1 N-(diphenylmethylene)benzamide 

Relevant articles and documents

Rhodium-catalyzed arylation and alkenylation of imines with organostannanes

A rhodium complex catalyzed the addition of aryl- and alkenyl-stannanes to activated aldimines under mild and neutral conditions, affording the corresponding amines in good yields.

Method for synthesizing amide compound by taking nitrile and diaryl methane as raw materials

The invention discloses a method for synthesizing an amide compound by taking nitrile and diaryl methane as raw materials, the method comprises the following steps: taking diaryl methane as a reaction raw material, nitrile as a raw material and a solvent, 2, 3-dichloro-5, 6-dinitrile group-1, 4-benzoquinone (DDQ) and tert-butyl nitrite (TBN) as catalysts, acid as an auxiliary agent and oxygen as an oxidizing agent, reacting under the conditions of normal temperature, normal pressure and blue light irradiation, and after the reaction is finished, carrying out separation treatment to obtain the amide compound. According to the method, the problem of metal residues in the product can be solved, oxygen is used as a terminal oxidizing agent, the method is environmentally friendly, and energy can be saved.

Metal-free transamidation of benzoylpyrrolidin-2-one and amines under aqueous conditions

N-Acyl lactam amides, such as benzoylpyrrolidin-2-one, benzoylpiperidin-2-one, and benzoylazepan-2-one reacted with amines in the presence of DTBP and TBAI to afford the transamidated products in good yields. The reactions were conducted under aqueous conditions and good functional group tolerance was achieved. Both aliphatic and aromatic primary amines displayed good activity under metal-free conditions. A radical reaction pathway is proposed.

Preparation method of photocatalytic N-alkylamide compound

The invention belongs to the technical field of organic synthesis, and provides a preparation method of an N-alkylamide compound. According to the method, a dioxazolone compound and an alkane derivative are used as raw materials, a manganese catalyst and an additive react for 12-24 hours in an organic solvent under a mild condition under photocatalysis, and the product is converted into an N-alkylamide compound. The method has the beneficial effects that the raw materials are cheap and easy to obtain, the conditions are mild, the method is environment-friendly, the possibility of industrialization is realized, and the yield of the N-alkylamide compound is high; the N-alkylamide compound can be further functionalized to obtain various compounds, and is applied to development and research of natural products, functional materials and fine chemicals.