148505-39-9

Basic information

• Product Name: N-[4-[[4-[2-(4-Nitrophenoxy)ethyl]-1-piperazinyl]carbonyl]phenyl]methanesulfonamide
• Synonyms: N-[4-[[4-[2-(4-Nitrophenoxy)ethyl]-1-piperazinyl]carbonyl]phenyl]methanesulfonamide
• CAS NO: 148505-39-9
• Molecular Weight: 448.5
• Mol File: 148505-39-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[4-[[4-[2-(4-Nitrophenoxy)ethyl]-1-piperazinyl]carbonyl]phenyl]methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-[[4-[2-(4-Nitrophenoxy)ethyl]-1-piperazinyl]carbonyl]phenyl]methanesulfonamide(148505-39-9)
• EPA Substance Registry System: N-[4-[[4-[2-(4-Nitrophenoxy)ethyl]-1-piperazinyl]carbonyl]phenyl]methanesulfonamide(148505-39-9)

Safety Data

• Hazardous Substances Data: 148505-39-9(Hazardous Substances Data)

Upstream product

• 13889-98-0 N-acetylpiperidine 
• 13288-06-7 1-(2-bromoethoxy)-4-nitrobenzene 
• 584-08-7 potassium carbonate 

Downstream Products

• 148505-49-1 N-[4-[[4-[2-(4-aminophenoxy)ethyl]-1-piperazinyl]carbonyl]phenyl]methanesulfonamide 

Relevant articles and documents

Piperidinyl and piperazinyl derivatives

Compounds of the formula: STR1 in which R1 is alkylsulfonamido of 1 to 6 carbon atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO2,--CN, 1-imidazolyl or 1,2,4-triazol-1-yl; Y is STR2 --CH2 --, --O--, --S--, or --SO2 --; X is --CH= or --N=; R2 is hydrogen when n is 0, otherwise it is hydrogen or --OH; n is one of the integers 0, 1, 2, 3, 4, 5 or 6; A is STR3 where R3 is alkylsulfonamido of 1 to 6 carbons atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO2, --CN, 1-imidazolyl or 1,2,4-triazol-1-yl; or STR4 where R4 is hydrogen or alkyl of 1 to 6 carbon atoms; with the provisos that; a) X is --CH= when Y is STR5 --O-- or --S-- and when Y is STR6 and R2 is --OH; b) X is --N= when A is STR7 c) A is STR8 when Y is --S-- or --SO2 -- and X is --CH=, and their pharmaceutically acceptable salts are Class III antiarrhythmic agents.