1486-57-3Relevant articles and documents
Synthesis of quercetin glycosides and their α-glucosidase inhibitory activities
Xu, Bixue,Liang, Guangyi,Wen, Zhonghang,Hu, Zhanxin,Yuan, Jie,Chen, Hongju,Zhang, Limei
, p. 1245 - 1260 (2016)
A series of quercetin glycosides as the analogues of 3,5,5'- Trimethyl-7-O-β-D-glucopyranosylquercetin (8) were synthesized, their structures were confirmed by 1H NMR, 13C NMR and MS. The inhibitory activities of those compounds against α-glucosidase were evaluated in vitro, in particular, the compounds V-c and V-d-2 showed promising bioactivities with IC50 of 19.4 μmol·L-1 and 19.7 μmol·L-1, are much higher than 8 (IC50 > 100 μmol·L-1). This research will provide a reference in the study of the synthetic methods and hypoglycemic activity for the quercetin glycosides.
Flavone glycoside derivatives, and preparation method and application thereof
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, (2016/10/08)
The invention discloses flavone glycoside derivatives which are compounds with a general structural formula I shown in the description, and pharmaceutically acceptable salts or hydrates thereof, including racemates, optical isomers and epimers of the deri
Synthesis of (2-amino)ethyl derivatives of quercetin 3-O-methyl ether and their antioxidant and neuroprotective effects
Lee, Young Hun,Kim, Hyoung Ja,Yoo, Ho,Jung, Seo Yun,Kwon, Bong Jin,Kim, Nam-Jung,Jin, Changbae,Lee, Yong Sup
, p. 4970 - 4979 (2015/08/03)
Reactive oxygen species have been implicated in several diseases, particularly in ischemia-reperfusion injury. Quercetin 3-O-methyl ether has been reported to show potent antioxidant and neuroprotective activity against neuronal damage induced by reactive