14866-28-5 Usage
Description
1-(2,4-dichlorophenyl)ethane-1,2-diol, also known as Isoconazole Impurity 7, is a chemical compound derived from Isoconazole (I798250), which is an antibacterial and antifungal agent. 1-(2,4-dichlorophenyl)ethane-1,2-diol possesses a unique molecular structure with two hydroxyl groups and a 2,4-dichlorophenyl group attached to an ethanedioic backbone, which may contribute to its potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
1-(2,4-dichlorophenyl)ethane-1,2-diol is used as an impurity in the production of Isoconazole, an antibacterial and antifungal agent. Its presence in the final product is crucial for the effectiveness of the medication, as it contributes to the overall activity against various bacterial and fungal infections, particularly in the treatment of vaginitis.
Used in Chemical Research:
1-(2,4-dichlorophenyl)ethane-1,2-diol can be utilized as a starting material or intermediate in the synthesis of other related compounds with potential applications in various fields, such as pharmaceuticals, agrochemicals, or materials science. Its unique structure and functional groups make it an interesting candidate for further exploration and development.
Used in Quality Control and Analysis:
As an impurity of Isoconazole, 1-(2,4-dichlorophenyl)ethane-1,2-diol can be used in the quality control and analysis of the final product. By monitoring the levels of this impurity, manufacturers can ensure the safety, efficacy, and consistency of the antibacterial and antifungal agent, ultimately contributing to the overall quality of the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 14866-28-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,8,6 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 14866-28:
(7*1)+(6*4)+(5*8)+(4*6)+(3*6)+(2*2)+(1*8)=125
125 % 10 = 5
So 14866-28-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8Cl2O2/c9-5-1-2-6(7(10)3-5)8(12)4-11/h1-3,8,11-12H,4H2
14866-28-5Relevant articles and documents
Ru-MACHO-Catalyzed Highly Chemoselective Hydrogenation of α-Keto Esters to 1,2-Diols or α-Hydroxy Esters
Gao, Shaochan,Tang, Weijun,Zhang, Minghui,Wang, Chao,Xiao, Jianliang
supporting information, p. 1748 - 1752 (2016/07/06)
A ruthenium pincer catalyst has been shown to be highly effective for the hydrogenation of a wide range of α-keto esters, affording either diols or hydroxy esters depending on the choice of reaction conditions. Strong base, high temperature, and pressure favor the formation of diols whilst the opposite is true for the hydroxy esters.
