148679-64-5

Basic information

• Product Name: [1,2-Bis-(3,4-dimethoxy-phenyl)-ethyl]-(2-phenylsulfanyl-ethyl)-amine
• Synonyms: [1,2-Bis-(3,4-dimethoxy-phenyl)-ethyl]-(2-phenylsulfanyl-ethyl)-amine
• CAS NO: 148679-64-5
• Molecular Weight: 453.602
• Mol File: 148679-64-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [1,2-Bis-(3,4-dimethoxy-phenyl)-ethyl]-(2-phenylsulfanyl-ethyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [1,2-Bis-(3,4-dimethoxy-phenyl)-ethyl]-(2-phenylsulfanyl-ethyl)-amine(148679-64-5)
• EPA Substance Registry System: [1,2-Bis-(3,4-dimethoxy-phenyl)-ethyl]-(2-phenylsulfanyl-ethyl)-amine(148679-64-5)

Safety Data

• Hazardous Substances Data: 148679-64-5(Hazardous Substances Data)

Upstream product

• 2014-75-7 2-(phenylthio)ethanamine 
• 4927-55-3 1,2-bis(3,4-dimethoxyphenyl)ethanone 
• 41010-04-2 4-nitro-2-(2-(phenylthio)ethyl)isoindoline-1,3-dione 

Downstream Products

• 523-02-4 2,3,10,11-tetramethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[3,2-a]isoquinoline 
• 148679-66-7 (2-Benzenesulfinyl-ethyl)-[1,2-bis-(3,4-dimethoxy-phenyl)-ethyl]-carbamic acid methyl ester 
• 148679-69-0 2-(2-Benzenesulfinyl-ethyl)-3-(3,4-dimethoxy-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline 
• 148679-67-8 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-N-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline 
• 1699-51-0 laudanosine 
• 13074-31-2 Tetrahydropapaverine 
• 210696-91-6 N-(2-Benzenesulfinyl-ethyl)-N-[1,2-bis-(3,4-dimethoxy-phenyl)-ethyl]-formamide 
• 50722-30-0 1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbaldehyde 
• 792843-84-6 2-(3,4-dimethoxy-phenyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine 
• 210696-90-5 N-[1,2-Bis-(3,4-dimethoxy-phenyl)-ethyl]-N-(2-phenylsulfanyl-ethyl)-formamide 
• 148679-68-9 3-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-2-(2-phenylsulfanyl-ethyl)-1,2,3,4-tetrahydro-isoquinoline 

Relevant articles and documents

A new regioselective synthesis of isopavine and pavine alkaloids via double cyclization of N-(1,2-diarylethyl)-N-(2-phenylsulfinylethyl)formamide

Pummerer reaction of N-[1,2-(3,4-dimethoxyphenyl)ethyl]-N-(2-phenylsulfinylethyl)formamide (9) using trifluoroacetic anhydride and boron trifluoride etherate caused double cyclization to give N-formylisopavine (21). Acid catalyzed cyclization of the 1,2-dihydroisoquinoline (23) prepared from 4-phenylthio-1,2,3,4-tetrahydroisoquinoline (11) gave N-formylpavine (26). LiAlH4 reduction of the N-formates (21 and 26) gave (±)-O-methylthalisopavine (4) and (±)-argemonine (5), respectively.