148842-98-2

Basic information

• Product Name: Acetamide, N-[2-(1-hydroxy-2-propynyl)phenyl]- (9CI)
• Synonyms: Acetamide, N-[2-(1-hydroxy-2-propynyl)phenyl]- (9CI)
• CAS NO: 148842-98-2
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21
• Mol File: 148842-98-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acetamide, N-[2-(1-hydroxy-2-propynyl)phenyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-(1-hydroxy-2-propynyl)phenyl]- (9CI)(148842-98-2)
• EPA Substance Registry System: Acetamide, N-[2-(1-hydroxy-2-propynyl)phenyl]- (9CI)(148842-98-2)

Safety Data

• Hazardous Substances Data: 148842-98-2(Hazardous Substances Data)

Upstream product

• 5344-90-1 2-Aminobenzyl alcohol 
• 20939-77-9 2-acetamidobenzyl alcohol 
• 13493-47-5 N-(2-formylphenyl)acetamide 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 1642593-32-5 (E)-3-(2-acetamidophenyl)-N-tosylacrylamide 
• 25770-52-9 (E)-4-methyl-N-(quinolin-2(1H)-ylidene)benzenesulfonamide 
• 700347-18-8 (E)-N-(quinolin-2(1H)-ylidene)-4-(trifluoromethyl)benzenesulfonamide 
• 1642627-97-1 (E)-N-(quinolin-2(1H)-ylidene)-2-(trifluoromethyl)benzenesulfonamide 
• 33757-75-4 (E)-N-(quinolin-2(1H)-ylidene)benzenesulfonamide 
• 1642593-31-4 1-(2-acetamidophenyl)prop-2-ynyl acetate 

Relevant articles and documents

A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines

We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SO2CF3 groups. The protocol is metal-, catalyst- and irradiation-free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild conditions of the process allow the tolerance of a wide range of functional groups.

Tandem Cu-catalyzed ketenimine formation and intramolecular nucleophile capture: Synthesis of 1,2-dihydro-2-iminoquinolines from 1-(o-acetamidophenyl) propargyl alcohols

The copper-catalyzed ketenimine formation reaction of 1-(o-acetamidophenyl) propargyl alcohols with various sulfonyl azides is found to undergo a concomitant intramolecular nucleophile attack to generate 1,2-dihydro-2- iminoquinolines after aromatization (via elimination of acetyl and hydroxy groups) and tautomerization. The reaction produces 4-substituted and 3,4-unsubstituted title compounds in moderate to good yields under mild reaction conditions.