148870-56-8 Usage
Description
Bicyclo[4.2.0]octa-1,3,5-triene-7-MethanaAmine, 3,4-diMethoxy-N-Methylis a complex organic compound with a unique bicyclic structure and various functional groups. It is characterized by its bicyclic framework, methoxy substitutions, and a nitrogen-containing side chain. Bicyclo[4.2.0]octa-1,3,5-triene-7-MethanaMine, 3,4-diMethoxy-N-Methylis known for its presence as an impurity in Ivabradine, a medication used for certain heart conditions.
Uses
Used in Pharmaceutical Industry:
Bicyclo[4.2.0]octa-1,3,5-triene-7-MethanaAmine, 3,4-diMethoxy-N-Methylis used as an impurity in the production of Ivabradine (I940500) for its antianginal properties. It plays a role in the development and formulation of heart medications, specifically those aimed at treating angina and related cardiovascular conditions.
As an impurity in Ivabradine, this compound may also contribute to the overall efficacy and safety profile of the drug. Understanding its presence and effects can help in optimizing the drug's performance and minimizing potential side effects. Additionally, further research into its properties and interactions may reveal new therapeutic applications or opportunities for its use in other areas of the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 148870-56-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,8,7 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 148870-56:
(8*1)+(7*4)+(6*8)+(5*8)+(4*7)+(3*0)+(2*5)+(1*6)=168
168 % 10 = 8
So 148870-56-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H17NO2/c1-13-7-9-4-8-5-11(14-2)12(15-3)6-10(8)9/h5-6,9,13H,4,7H2,1-3H3
148870-56-8Relevant articles and documents
AN IMPROVED PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
-
Paragraph 15; 16, (2019/11/12)
: Disclosed herein is an improved process for the preparation of Ivabradine and pharmaceutically acceptable salts thereof. The invention more particularly disclosesthe synthesis of key intermediates viz.,(S)-N-[(4,5-dimethoxybenzocydobut-l-yl)-methyl]-N- (methyl)amine hydrochloride of Formula-II and 3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzapin-2-one of Formula-III, and its use in industrial synthesis of Ivabradine and pharmaceutically acceptable salts thereof.
PROCESS FOR THE SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID
-
, (2014/06/24)
Process for the synthesis of the compound of formula (I): Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.
PROCESS FOR THE SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID
-
Paragraph 0058-0059, (2014/05/07)
Process for the synthesis of the compound of formula (I): Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.
