149159-43-3

Basic information

• Product Name: 2,3-bis(4-fluorophenyl)pyrido[2,3-b]pyrazine
• Synonyms: 2,3-bis(4-fluorophenyl)pyrido[2,3-b]pyrazine
• CAS NO: 149159-43-3
• Molecular Weight: 319.313
• Mol File: 149159-43-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,3-bis(4-fluorophenyl)pyrido[2,3-b]pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-bis(4-fluorophenyl)pyrido[2,3-b]pyrazine(149159-43-3)
• EPA Substance Registry System: 2,3-bis(4-fluorophenyl)pyrido[2,3-b]pyrazine(149159-43-3)

Safety Data

• Hazardous Substances Data: 149159-43-3(Hazardous Substances Data)

Upstream product

• 452-58-4 2,3-Diaminopyridine 
• 579-39-5 1,2-bis(4-fluorophenyl)ethane-1,2-dione 

Relevant articles and documents

Covalent anchoring of copper-Schiff base complex into SBA-15 as a heterogeneous catalyst for the synthesis of pyridopyrazine and quinoxaline derivatives

The ordered mesoporous silica SBA-15 was covalently anchored with copper (II) Schiff base complex to afford Cu(II)-Schiff base/SBA-15 catalyst. Powder X-ray diffraction, nitrogen adsorption-desorption analyses and TEM image confirm not only the retaining of support properties after anchoring but also the existence of void space in nanometer scale which result in good catalytic activity in the synthesis of pyridopyrazine and quinoxaline derivatives.

An iron Schiff base complex loaded mesoporous silica nanoreactor as a catalyst for the synthesis of pyrazine-based heterocycles

An iron Schiff base complex was encapsulated in SBA-15 mesoporous silica to afford a Fe(III)-Schiff base/SBA-15 heterogeneous nanocatalyst for the synthesis of pyridopyrazine and quinoxaline heterocycles. These reactions proceeded in water with excellent yields. The catalyst was characterized by physico-chemical and spectroscopic methods and found to retain the characteristic channel structures of the SBA-15, allowing good accessibility of the encapsulated metal complex.

ZrOCl2.8H2O in water: An efficient catalyst for rapid one-pot synthesis of pyridopyrazines, pyrazines and 2,3-disubstituted quinoxalines

Zirconium(IV) oxide chloride was found to be a rapid and efficient catalyst for the synthesis of pyrazines and 2,3-disubstituted quinoxalines in water. A variety of pyridopyrazine and 2,3-disubstituted quinoxaline derivatives are readily prepared in high yields under green conditions by cyclocondensation of the desired 1,2-diamine and 1,2-diketone using a catalytic amount of zirconium(IV) oxide chloride in water. Less active diamines, such as 2,3- and 3,4-diaminopyridines took part in this protocol to provide the desired products in good to excellent yields.