149221-40-9

Basic information

• Product Name: 2-Cyclopenten-1-one, 3-[(phenylmethyl)amino]-
• CAS NO: 149221-40-9
• Molecular Formula: C12H13NO
• Molecular Weight: 187.241
• Mol File: 149221-40-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Cyclopenten-1-one, 3-[(phenylmethyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-one, 3-[(phenylmethyl)amino]-(149221-40-9)
• EPA Substance Registry System: 2-Cyclopenten-1-one, 3-[(phenylmethyl)amino]-(149221-40-9)

Safety Data

• Hazardous Substances Data: 149221-40-9(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 205999-79-7 3-oxocyclopent-1-en-1-yl 4-methylbenzenesulfonate 
• 930-30-3 cyclopent-2-enone 
• 622-79-7 benzyl azide 
• 5870-62-2 3-hydroxy-2-cyclopenten-1-one 
• 3859-41-4 1,3-cyclopentadione 

Downstream Products

• 183674-21-7 N-benzyl-N-(3-oxocyclopent-1-enyl)pent-4-enamide 
• 28566-12-3 3-amino-cyclopent-2-en-1-one 
• 1402907-02-1 1-benzyl-1,2,6,7-tetrahydro-2-methyl-2-(4-methylpent-3-enyl)-5H-cyclopenta[b]pyridin-5-one 
• 1402907-01-0 1-benzyl-1,2,6,7-tetrahydro-2,2-dimethyl-5H-cyclopenta[b]pyridin-5-one 

Relevant articles and documents

Lewis Acid-Mediated Reactions of Alkyl Azides with α,β- Unsaturated Ketones

(Matrix presented) Alkyl azides react with saturated ketones upon treatment with Lewis acids to afford ring-expansion products through the azido-Schmidt reaction, but this reaction does not proceed when α,β-unsaturated ketones are used. In this study, alk

Synthesis of β-triazolylenones via metal-free desulfonylative alkylation of N-tosyl-1,2,3-triazoles

Desulfonylative alkylation of N-tosyl-1,2,3-triazoles under metal-free conditions leading to β-triazolylenones is reported here. The present study encompasses the synthesis of triazoles with a new substitution pattern in a single step from cyclic 1,3-dicarbonyl compounds and N-tosyl triazole in moderate to high yields. Our synthesis takes place with complete regioselectivity as confirmed by crystallographic analysis which is rationalized by a suitable mechanistic proposal. This method provides an efficient, versatile and straightforward strategy towards the synthesis of new functionalized 1,2,3-triazoles.

Cu catalyzed cross-dehydrogenative coupling reaction for the synthesis of 3-hydroxy-2-pyrrolidinones

A new convenient strategy for the synthesis of 3-hydroxy-2-pyrrolidinone derivatives featuring regioselective C–C coupling has been developed. This is a Cu (II) catalyzed cross dehydrogenative coupling (CDC) involving enamino-ketones of benzyl amines and di-alkyl acetylenedicarboxylate, followed by cyclization by primary amines. TBHP (tert-butyl hydroperoxide) has been used as the oxidant to promote the coupling protocol. This synthetic route principally demonstrates the scope of CDC reaction and also applicable to gram-scale synthesis.