14933-25-6 Usage
General Description
3-Chloro-4-hydroxy-1H-quinolin-2-one is a chemical compound with the molecular formula C9H6ClNO2. It is a synthetic heterocyclic compound and a chlorinated derivative of 4-hydroxyquinoline. 3-Chloro-4-hydroxy-1H-quinolin-2-one is commonly used as an intermediate in the synthesis of pharmaceuticals and fine chemicals. It has also been studied for its potential biological activities such as anti-inflammatory, antifungal, and anticancer properties. Additionally, 3-Chloro-4-hydroxy-1H-quinolin-2-one has been used as a building block for the development of new drugs and agrochemicals due to its versatile reactivity and pharmacological potential.
Check Digit Verification of cas no
The CAS Registry Mumber 14933-25-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,3 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14933-25:
(7*1)+(6*4)+(5*9)+(4*3)+(3*3)+(2*2)+(1*5)=106
106 % 10 = 6
So 14933-25-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H6ClNO2/c10-7-8(12)5-3-1-2-4-6(5)11-9(7)13/h1-4H,(H2,11,12,13)
14933-25-6Relevant articles and documents
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George,T.,Tahilramani,R.
, p. 1007 - 1010 (1968)
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Ylides of Heterocycles, VIII. Reactions of Iodonium-Ylides with Acids
Pongratz, Erik,Kappe, Thomas
, p. 231 - 242 (2007/10/02)
The reaction of various organic and inorganic acids (HX) with iodonium ylides 2 leads to nucleophilic substitution of the iodobenzene substituent by the anion X(-) to yield the heterocycles 5.Some of them are hydrolyzed to the hydroxy compounds 3 or reduced to the starting compounds 1 under the reaction conditions.Reaction of the iodonium ylide 2b with monomethyl sulfate gives the salt 9, which with bases undergoes nucleophilic substitution to compounds 8 and 10-12, respectively, or is converted to 2b again. - Keywords: 3-Acetoxy-4-hydroxy-2-quinolones; 2-Oxoquinoline-4-olates; 3-Substituted 4-hydroxy-2-quinolones