149648-49-7Relevant articles and documents
Inhibitors of histone deacetylase suppress the growth of MCF-7 breast cancer cells
Schmidt, Kathrin,Gust, Ronald,Jung, Manfred
, p. 353 - 357 (1999)
Inhibitors of histone deacetylase are attracting increasing interest due to their influence on transcription, differentiation, and apoptosis. We have investigated two synthetic inhibitors 3 and 4 of histone deacetylase and the natural product inhibitor tr
HISTONE DEACETYLASE INHIBITORS
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Page/Page column 47; fig. 13, (2010/04/23)
In recognition of the need to develop novel therapeutic agents, the present invention provides novel histone deacetylase inhibitors. These compounds include an ester bond making them sensitive to deactivation by esterases. Therefore, these compounds are p