1496541-78-6

Basic information

• Product Name: dimethyl 2-(3-(4-nitrophenyl)-3-oxopropyl)-2-(trifluoromethyl)malonate
• CAS NO: 1496541-78-6
• Molecular Weight: 377.274
• Mol File: 1496541-78-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl 2-(3-(4-nitrophenyl)-3-oxopropyl)-2-(trifluoromethyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-(3-(4-nitrophenyl)-3-oxopropyl)-2-(trifluoromethyl)malonate(1496541-78-6)
• EPA Substance Registry System: dimethyl 2-(3-(4-nitrophenyl)-3-oxopropyl)-2-(trifluoromethyl)malonate(1496541-78-6)

Safety Data

• Hazardous Substances Data: 1496541-78-6(Hazardous Substances Data)

Upstream product

• 5838-00-6 methyl dimethyl 2-(trifluoromethyl)propanedioate 
• 68165-35-5 1-(3-nitrophenyl)-2-propen-1-one 

Relevant articles and documents

Organocatalytic reactions of α-trifluoromethylated esters with terminal alkenes at room temperature

CF3-containing esters smoothly reacted with electron-deficient alkenes in the presence of a phosphine (2-dicyclohexylphosphino-2′, 4′,6′-triisopropylbiphenyl) organocatalyst at room temperature in an aerobic atmosphere. These Michael reactions efficiently provided products with a CF3 quaternary carbon center.