149731-53-3

Basic information

• Product Name: diphenyl(2,4,6-trimethylbenzyl)phosphine oxide
• Synonyms: diphenyl(2,4,6-trimethylbenzyl)phosphine oxide
• CAS NO: 149731-53-3
• Molecular Weight: 334.398
• Mol File: 149731-53-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: diphenyl(2,4,6-trimethylbenzyl)phosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: diphenyl(2,4,6-trimethylbenzyl)phosphine oxide(149731-53-3)
• EPA Substance Registry System: diphenyl(2,4,6-trimethylbenzyl)phosphine oxide(149731-53-3)

Safety Data

• Hazardous Substances Data: 149731-53-3(Hazardous Substances Data)

Upstream product

• 4559-70-0 Diphenylphosphine oxide 
• 4170-90-5 2,4,6-trimethylbenzyl alcohol 
• 1079-66-9 chloro-diphenylphosphine 
• 487-68-3 mesytaldehyde 
• 913724-93-3 diphenyl(2,4,6-trimethylbenzyl)phosphine 

Downstream Products

• 75980-60-8 (2,4,6-trimethylbenzoyl)diphenylphosphine oxide 

Relevant articles and documents

Palladium-catalyzed benzylic substitution of benzyl carbonates with phosphorus nucleophiles

A wide range of benzyl carbonates reacted with dimethyl phosphonate or diphenylphosphine oxide in the presence of the palladium catalyst, [Pd(η3-allyl)Cl]2DPEphos, to give dimethyl benzylphosphonates and benzyldiphenylphosphine oxides in high yields. The catalytic phosphonylation was applied to the one-pot synthesis of alkenes from the benzyl esters.

Practical way for the synthesis of phosphine oxides and phosphine sulfides from benzyl alcohol derivatives

The reaction of benzyl alcohol derivatives with Ph2PI generated in situ from Ph2PCl and NaI provides a facile way to the synthesis of pentavalent phosphine compounds with moderate to excellent yields.