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149949-05-3

149949-05-3

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149949-05-3 Usage

Uses

A derivative of Simvastatin. An isomer of 3’(S)-Hydroxy Simvastatin.

Check Digit Verification of cas no

The CAS Registry Mumber 149949-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,9,4 and 9 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 149949-05:
(8*1)+(7*4)+(6*9)+(5*9)+(4*4)+(3*9)+(2*0)+(1*5)=183
183 % 10 = 3
So 149949-05-3 is a valid CAS Registry Number.

149949-05-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5'(S)-Hydroxy Simvastatin DISCONTINUED

1.2 Other means of identification

Product number -
Other names [(1S,3R,4S,7S,8S)-4-hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,4,7,8-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:149949-05-3 SDS

149949-05-3Upstream product

149949-05-3Downstream Products

149949-05-3Relevant articles and documents

Autooxidation of simvastatin

Smith,DiMichele,Colwell Jr.,Dezeny,Douglas,Reamer,Verhoeven

, p. 4447 - 4462 (1993)

Autooxidation of the cholesterol-lowering agent simvastatin in ethylene dichloride solution with an azo-type free-radical initiator was investigated in kinetic studies using HPLC. The primary products were oligomers, with peroxide groups within the backbone chain, and some monomeric epoxides. These and several secondary products were isolated chromatographically and identified spectroscopically. A reaction scheme was proposed in which the oligomers arise from competitive hydrogen abstraction and addition reactions of oligomeric free radicals with simvastatin while the epoxides arise from homolytic peroxide cleavage.

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