149981-20-4 Usage
Description
3,7-Dimethyl-8-p-sulfophenylxanthine is a white solid compound that functions as a weak water-soluble A2 adenosine receptor antagonist. It is characterized by its UV lmax values in methanol, which are 203 nm (4.45), 239 nm (4.34), and 301 nm (4.26).
Uses
Used in Pharmaceutical Industry:
3,7-Dimethyl-8-p-sulfophenylxanthine is used as a pharmaceutical agent for its A2 adenosine receptor antagonist properties. Its application is primarily due to its ability to modulate the A2 adenosine receptor, which plays a role in various physiological processes and can be targeted for therapeutic purposes.
Used in Research and Development:
In the field of research and development, 3,7-Dimethyl-8-p-sulfophenylxanthine is utilized as a tool compound to study the role of A2 adenosine receptors in cellular processes and to develop new drugs targeting these receptors. Its weak water solubility and specific UV absorption characteristics make it a valuable compound for experimental studies.
Used in Drug Design and Synthesis:
3,7-Dimethyl-8-p-sulfophenylxanthine serves as a starting point or a structural component in the design and synthesis of new drugs targeting the A2 adenosine receptor. Its chemical properties and antagonistic activity can be leveraged to create more potent and selective compounds for therapeutic use.
Used in Diagnostic Applications:
Due to its UV absorption characteristics, 3,7-Dimethyl-8-p-sulfophenylxanthine can be employed in diagnostic applications where the detection and quantification of A2 adenosine receptors are required. Its specific absorption peaks can be used to identify and measure the presence of these receptors in biological samples.
Check Digit Verification of cas no
The CAS Registry Mumber 149981-20-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,9,8 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 149981-20:
(8*1)+(7*4)+(6*9)+(5*9)+(4*8)+(3*1)+(2*2)+(1*0)=174
174 % 10 = 4
So 149981-20-4 is a valid CAS Registry Number.
149981-20-4Relevant articles and documents
Effect of Trifluoromethyl and Other Substituents on Activity of Xanthines at Adenosine Receptors
Jacobson, Kenneth A.,Shi, Dan,Gallo-Rodriguez, Carola,Manning, Malcolm,Mueller, Christa,et al.
, p. 2639 - 2644 (2007/10/02)
An aryl p-(trifluoromethyl) substituent increases the affinity of 1,3-disubstituted 8-phenylxanthines at A2a-adenosine receptors, while having little effect on affinity at A1-adenosine receptors.In contrast, an aryl p-(trifluoromethy
