1501963-64-9

Basic information

• Product Name: 4-(4-(trifluoromethoxy)phenoxy)piperidine hydrochloride
• CAS NO: 1501963-64-9
• Molecular Weight: 297.705
• Mol File: 1501963-64-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(4-(trifluoromethoxy)phenoxy)piperidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-(trifluoromethoxy)phenoxy)piperidine hydrochloride(1501963-64-9)
• EPA Substance Registry System: 4-(4-(trifluoromethoxy)phenoxy)piperidine hydrochloride(1501963-64-9)

Safety Data

• Hazardous Substances Data: 1501963-64-9(Hazardous Substances Data)

Upstream product

• 828-27-3 4-Trifluoromethoxyphenol 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 287952-66-3 tert-butyl 4-(4-(trifluoromethoxy)phenoxy)piperidin-1-carboxylate 

Relevant articles and documents

Method for preparing highly pure Delamanid intermediate

The invention provides a method for preparing a highly pure delamanid intermediate. The intermediate is 4-[4-(trifluoromethoxy)phenoxyl]piperidine. Hydrogen chloride is dissolved in ethyl acetate in a Boc group removal step, and the dissolvability difference between the above product and impurities in ethylene acetate is used to carry out purification, so a column chromatography purifying method using tedious operation is avoided, the final product with high yield and high purity is also obtained, the production cost is reduced, and the method is suitable for industrial large-scale production.

Synthesis and activity of selective MMP inhibitors with an aryl backbone

A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described. (C) 2000 Elsevier Science Ltd.