150535-67-4Relevant articles and documents
Cyclic Transformations of 5-Aryl(or Benzyl)-3-(2-bromoethyl-1,3,4-oxadiazol-2(3H)-ones into 1-Aminoimidazolidin-2-one and 5,6-Dihydro-4H-1,3,4-oxadiazine Derivatives
Milcent, Rene,Barbier, Geo
, p. 1081 - 1084 (2007/10/02)
5-Aryl(or benzyl)-3-(2-bromoethyl)-1,3,4-oxadiazol-2(3H)-ones 3 have been prepared.They were reacted with secondary alkylamines without any change of the heterocycle to give amino derivatives 6, but with primary alkylamines, cyclic transformation occurred to give 1-acylamino-3-alkylimidazolidin-2-ones 7.In the presence of sodium alcoholate, bromo compounds 3 were transformed into 2-aryl(or benzyl)-4-alkoxycarbonyl-5,6-dihydro-4H-1,3,4-oxadiazines 9.