150766-86-2 Usage
Description
4-BROMOMETHYLBIPHEBYL-2'-CARBOXYLIC ACID is an organic compound with a unique chemical structure that features a bromomethyl group and a carboxylic acid functional group. It is characterized by its molecular formula and is known for its potential applications in various industries due to its chemical properties.
Uses
Used in Pharmaceutical Industry:
4-BROMOMETHYLBIPHEBYL-2'-CARBOXYLIC ACID is used as an intermediate in the preparation of antihypertensive agents, which are medications designed to treat high blood pressure. Its chemical structure allows it to be a key component in the synthesis of these drugs, contributing to their effectiveness in managing hypertension.
Used in Chemical Synthesis:
4-BROMOMETHYLBIPHEBYL-2'-CARBOXYLIC ACID is also used as an impurity of Telmisartan (D294250), which is an angiotensin II receptor antagonist used to treat hypertension. Its presence in the synthesis process may affect the purity and quality of the final product, making it an important compound to consider during the manufacturing of Telmisartan and other related pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 150766-86-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,7,6 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 150766-86:
(8*1)+(7*5)+(6*0)+(5*7)+(4*6)+(3*6)+(2*8)+(1*6)=142
142 % 10 = 2
So 150766-86-2 is a valid CAS Registry Number.
150766-86-2Relevant articles and documents
Method for preparing telmisartan and intermediates thereof
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Paragraph 0112-0113; 0115, (2017/08/31)
Disclosed is a telmisartan preparation method, characterized in that: 2-n-propyl-4-methyl-6-(1-methyl benzimidazole-2-yl) benzimidazole (compound I) and 4'-halomethyl diphenyl-2-substituted compound (compound II) conduct a nucleophilic substitution reaction to obtain a compound III; when R is COOH, the compound III is telmisartan; and when R is COOR' or CN, the compound III can be hydrolyzed to obtain telmisartan.
Method for preparing bromomenthyl-biphenyl derivatives
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, (2008/06/13)
The present invention relates to a process for the preparation of 4′-bromomethyl-biphenyl derivatives of the formula: by reacting a 4′-methyl-biphenyl derivative of the formula: with a brominating agent a in a hydrobromic acid/alkali metal bromate system in a two-phase medium, and under photo-iradiation, where R is as defined in the specification.
Process for producing 4-bromomethylbiphenyl compounds
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, (2008/06/13)
A process for the production of a compound of general formula STR1 wherein R represents cyano, carboxy which may be esterified or amidated or tetrazolyl which may be substituted, comprising brominating the corresponding methyl compound with a brominating agent such as N -bromoacetamide, N-bromophtalimide, N-bromosuccinimide and so on in a halogenated hydrocarbon solvent in the presence of an azobis compound.
