150930-84-0

Basic information

• Product Name: 10-desacetoxybaccatin
• Synonyms: 10-desacetoxybaccatin
• CAS NO: 150930-84-0
• Molecular Weight: 528.599
• Mol File: 150930-84-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 10-desacetoxybaccatin(CAS DataBase Reference)
• NIST Chemistry Reference: 10-desacetoxybaccatin(150930-84-0)
• EPA Substance Registry System: 10-desacetoxybaccatin(150930-84-0)

Safety Data

• Hazardous Substances Data: 150930-84-0(Hazardous Substances Data)

Upstream product

• 149140-53-4 C₄₂H₄₉F₅O₁₁SSi 
• 115437-18-8 7-triethylsilyl-10-deacetylbaccatin III 
• 27548-93-2 baccatin III 
• 32981-86-5 10-deacetylbaccatin III 
• 149140-51-2 10-Deacetoxy-7-(triethylsilyl)baccatin III 

Downstream Products

• 150930-85-1 10-Deoxybaccatin 7-xanthate 
• 194718-11-1 7-[tert-butoxycarbonyl(methyl)amino]heptanoic acid 
• 149140-51-2 10-Deacetoxy-7-(triethylsilyl)baccatin III 

Relevant articles and documents

Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups

Process for the preparation of a derivative or analog of baccatin III or 10-desacetyl baccatin III having a C2 substituent other than benzoate and/or a C4 substituent other than acetate in which the C2 benzoate substituent and/or the C4 acetate substituen

Process for the preparation of 10-desacetoxybaccatin III

A process for abstracting a C10 hydroxy, acyloxy or sulfonyloxy substituent from a taxane in which the C10 hydroxy, acyloxy or sulfonyloxy substituted taxane is reacted with samarium diiodide.

Stereoselective Synthesis of 9β-Hydroxytaxanes via Reduction with Samarium Diiodide

Reaction of baccatin III and paclitaxel with samarium diiodide yielded the corresponding 10-deacetyl-9β-hydroxy derivatives.When 10-deacetylbaccatin III and docetaxel were subjected to the same reaction conditions the corresponding 9β-hydroxy and 10-dehyd